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We have 10 Evolution (cell) PhD Projects, Programmes & Scholarships

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Evolution (cell) PhD Projects, Programmes & Scholarships

We have 10 Evolution (cell) PhD Projects, Programmes & Scholarships

Cell biology and evolution of cancer metastasis

We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process. Read more

The role of regulatory evolution in phage ecology

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Multilevel selection on transposition rates in cancer

Cancer is an evolutionary process. Cells in a tumour vary due to mutation, and so over many generations they adapt in response to both intrinsic selective pressures (such as anoxia) and extrinsic selective pressures (such as chemotherapy). Read more

Control and inhibition of virus replication

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Noise and Evolution in Ageing Cellular Power Stations

PhD Project. Imperial College Mathematics. Student Background. Theoretical Physics, Mathematics/Statistics, Electrical Engineering, Computing (Biological knowledge not required). Read more

Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more

Optimizing phage-antibiotic-synergies to kill bacterial pathogens

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more
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