A multi-disciplined approach to understand membrane protein dynamics
BBSRC White Rose DTP
Dr S Muench, Dr C Pliotas
7 January 2019
Membrane proteins make up a significant part of the genome and are the target of ~30% of therapeutics and yet our structural and functional understanding often lags behind their soluble counterparts.
An integrated approach to the study of cellular interactions with amyloid
Astbury Centre for Structural Molecular Biology
Dr E W Hewitt, Prof S E Radford
Applications accepted all year round
The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
Biological physics of cell trafficking: Immune cell homing at the blood vessel wall
School of Biomedical Sciences
Dr R Richter
6 January 2019
Cell trafficking is vital to all multicellular life and key in diseases such as cancer. In this PhD project, you will devise new methods to study how immune cells that circulate in the blood stream find and bind to sites of inflammation and how cancer cells hijack the system to metastasize.
Bloom and bust: how do plants know when to stop flowering?
Centre for Plant Sciences
Dr T.A. Bennett
20 December 2018
We know a very large amount about the signals and mechanisms that lead to the initiation of flowering (the ‘floral transition’) in plants.