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University of Manchester, Faculty of Biology, Medicine and Health PhD Projects, Programs & Scholarships

We have 182 University of Manchester, Faculty of Biology, Medicine and Health PhD Projects, Programs & Scholarships

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  (A*STAR) Advanced deep-learning approaches for the early diagnosis of Congenital Heart Disease
  Dr D Talavera, Prof B Keavney
Application Deadline: 31 January 2019
Congenital Heart Disease (CHD) is a very common birth defect; it affects around 10 out of 1000 newborns worldwide. Survival into adulthood depends on various aspects.
  (A*STAR) Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function
  Prof M White, Dr A P Gilmore
Application Deadline: 31 January 2019
The project will investigate the control of NF-kB. This transcription factor is one of most important cell signalling systems in the body that controls inflammation and cell fate.
  (A*STAR) Can non-coding variants explain missing heritability in familial cancer?
  Prof B Newman, Prof G Evans, Dr M Smith
Application Deadline: 31 January 2019
Heterozygous germline variants in a number of tumour suppressor genes cause a spectrum of familial cancers, including early onset breast-ovarian cancer, and colorectal cancer.
  (A*STAR) Elucidating the role of polyamines in the epidermal skin barrier
  Dr S Cruickshank, Dr K Mace, Dr A Saunders
Application Deadline: 31 January 2019
Delayed wound healing is a major health issue affecting one in 50 people. The process of wound healing is a highly orchestrated process involving many cell types and regulatory networks.
  (A*STAR) Elucidation of molecular footprints of kidney fibrosis through integrative ‘omics’-based analysis
  Prof M Tomaszewski, Dr A Adamson, Prof A Woolf
Application Deadline: 31 January 2019
The fibrosis is a common pathway of structural damage in many kidney diseases. It is usually diagnosed when patients present with an irreversible drop in glomerular filtration rate.
  (A*STAR) Engineering of virus-like particles and novel multimeric assemblies as scaffolds for presentation of viral antigens
  Prof J P Derrick, Dr F Hayes
Application Deadline: 31 January 2019
This project will use structural vaccinology to investigate the potential for de novo engineering of large, synthetic macromolecular assemblies.
  (A*STAR) Investigating the role of Lrg1 in chronic kidney diseases
  Dr S Abraham, Prof M Tomaszewski, Dr N Ashton
Application Deadline: 31 January 2019
Chronic Kidney Disease (CKD) affects 10-20% of adults and is a major and increasing public health burden. CKD has several aetiologies that share a final common pathway characterised by an inadequate angiogenic response to renal hypoxia that could potentially serve to enhance the fibrotic phenotype.
  (A*STAR) Investigating transcriptional networks involved in blood lineage commitment
  Prof G Lacaud, Dr K Batta
Application Deadline: 31 January 2019
Transplantation of haematopoietic stem cells (HSCs) is a curative treatment for many malignant and non-malignant haematological disorders.
  (A*STAR) Programming human pancreatic progenitors for endocrine differentiation
  Prof N Hanley, Dr R Jennings
Application Deadline: 31 January 2019
There is an exciting opportunity for a PhD student to undertake highly distinctive, interdisciplinary research on human pancreatic beta cell differentiation.
  (A*STAR) Structure-based ligand discovery targeting protein kinases for antifungal therapy
  Dr L Tabernero, Dr M Bromley
Application Deadline: 31 January 2019
Fungal infections pose a serious threat to health affecting about 1.7 billion people worldwide and causing about 1.5 million deaths each year.
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