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The University of Manchester, Faculty of Biology, Medicine and Health PhD Projects, Programs & Scholarships

We have 245 The University of Manchester, Faculty of Biology, Medicine and Health PhD Projects, Programs & Scholarships

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  (BBSRC DTP) Functional and structural analysis of RBBP5: a histone tail modifier essential for development, disease and healthy ageing
  Dr G Poulin, Prof A Sharrocks, Dr A J Whitmarsh
Application Deadline: 31 January 2020

Funding Type

PhD Type

The genome is the blueprint of any living system. However, it is the regulation of gene expression that enables life. For transcription to take place, the molecular machinery involved has to access genomic DNA.
  (BBSRC DTP) How is our head formed? – alx1 homeobox gene and craniofacial development
  Dr S Herbert, Dr T Takahashi, Prof M Rattray
Application Deadline: 31 January 2020

Funding Type

PhD Type

The recent technological advancement of bioinformatics, next-generation sequencing and live imaging has transformed medical research.
  (BBSRC DTP) Improving 3D X-ray Imaging of Live Cells and Soft Tissues
  Dr M Sherratt, Prof S Cartmell
Application Deadline: 31 January 2020

Funding Type

PhD Type

Clinical X-ray imaging in three dimensions (commonly referred to as a CT scan) is a key diagnostic tool. Micro-computed X-ray tomography (microCT) has the potential to image relatively large biological samples in 3D at sub-micron resolution.
  (BBSRC DTP) Integrative statistical inference methods for eukaryotic gene regulation with applications to embryonic stem cell differentiation
  Dr I Iqbal, Prof M Rattray, Prof A Sharrocks
Application Deadline: 31 January 2020

Funding Type

PhD Type

Embryonic stem cells (ESCs) can differentiate into different cell types through intermediary cell states and deeper understanding of the regulatory control underlying these differentiation stages is a very important topic in the study of mammalian development (Yang et al., 2014 & 2019).
  (BBSRC DTP) Kinesin light chains: why so many?
  Prof V Allan, Prof M Ashe, Dr G Poulin
Application Deadline: 31 January 2020

Funding Type

PhD Type

Kinesin-1 is a microtubule motor that moves many cargoes within cells, and this transport is crucial for life and health.
  (BBSRC DTP) Light-dependent control of physiology via the brain’s central clock
  Dr T Brown, Dr D Bechtold, Dr G D'Agostino
Application Deadline: 31 January 2020

Funding Type

PhD Type

Aside from helping us perceive the world around us, light is a key regulator of physiology and behaviour due to its influence on the brains internal clock in the suprachiasmatic nuclei (SCN).
  (BBSRC DTP) Mapping Notch endocytic signalling pathways via quantitative proteomics in Drosophila melanogaster
  Prof S Hubbard, Dr M Baron, Prof C Mills
Application Deadline: 31 January 2020

Funding Type

PhD Type

Extracellular signalling allows cells to communicate with one another in the context of tissues and influence the fate of their neighbouring cells, transducing signals from the external environment to the nucleus to affect the expression of target genes.
  (BBSRC DTP) Mapping Notch trafficking using immunofluorescence and computer vision
  Dr N Thacker, Dr M Baron, Dr P Bromiley
Application Deadline: 31 January 2020

Funding Type

PhD Type

The functional regulation of proteins in cells is strongly related to their spatial distributions. This is particularly true of signalling proteins, which may be switched on and off by transfer between different locations.
  (BBSRC DTP) Mechanism of early steps in protein synthesis by cryoEM imaging of supramolecular complexes
  Dr A Roseman, Prof G D Pavitt, Prof C Baldock
Application Deadline: 31 January 2020

Funding Type

PhD Type

The aim of this project is to understand the mechanism and control of protein synthesis in eukaryotic cells at the molecular level, particularly focused around the role of the eukaryotic translation initiation factors eIF2, eIF5 and eIF2B.
  (BBSRC DTP) Metals and bacterial virulence: overcoming metal intoxication during infection
  Dr J Cavet, Dr D Linton, Prof J Lloyd
Application Deadline: 31 January 2020

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen, being the leading bacterial cause of human acute gastroenteritis and responsible for an estimated 0.5 billion cases each year.
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