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The University of Manchester, Faculty of Biology, Medicine and Health PhD Projects, Programs & Scholarships

We have 245 The University of Manchester, Faculty of Biology, Medicine and Health PhD Projects, Programs & Scholarships

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  (BBSRC DTP) The physiology and energetics of locomotion in turtles: linking performance from the organismal to the cellular level
  Dr J Codd, Dr G Galli
Application Deadline: 31 January 2020

Funding Type

PhD Type

Turtles have the most distinctive body plans of vertebrates (1). Turtles appear in the fossil record over 220 million years ago. Turtles are unique among vertebrates in that their whole body is enclosed within a rigid bony shell, composed of the carapace and plastron, that protects from predators.
  (BBSRC DTP) The role of clock dysfunction in obesity-related inflammation and insulin resistance
  Dr D Bechtold, Dr S Cruickshank, Dr I Iqbal
Application Deadline: 31 January 2020

Funding Type

PhD Type

Obesity is one of the biggest challenges to public health in the UK and across much of the world. The major threat is in obesity-related metabolic disturbances, which drive insulin resistance, type-2 diabetes, and cardiovascular disease.
  (BBSRC DTP) The role of collagen VI in the skeletal muscle stem cell niche using combined imaging approaches including Cryo-EM
  Prof C Baldock, Prof G Cossu, Dr A Roseman
Application Deadline: 31 January 2020

Funding Type

PhD Type

Collagen VI is a unique member of the collagen superfamily which has a short collagenous region but arrays of globular domains and assembles to form beaded microfibrils.
  (BBSRC DTP) The role of TARGET OF RAPAMYCIN in nutrition sensing and plantlet development in KalanchoĆ«
  Dr M Kim, Dr G Johnson
Application Deadline: 31 January 2020

Funding Type

PhD Type

How a cell determines its fate is a fundamental question in Biology. A differentiated somatic plant cell can be triggered to regain its pluripotency.
  (BBSRC DTP) Uncovering the mechanism(s) responsible for a novel neurite co-orientation process
  Dr C Dobson, Prof Keith Crutcher, Dr T Brown, Prof R Baines
Application Deadline: 31 January 2020

Funding Type

PhD Type

How do neurons decide where to grow? Although there is evidence for the role of growth factors (diffusible or bound) as well as electrical activity, the specific mechanism remains elusive.
  (BBSRC DTP) Understanding and predicting evolutionary change in HIV
  Prof S Lovell, Dr C Walton, Prof S Griffiths-Jones
Application Deadline: 31 January 2020

Funding Type

PhD Type

Our overall aim is to understand viral evolution, and the limitations on evolution that arise from the viral genome, proteome and structure-function relationships.
  (BBSRC DTP) Understanding mitochondrial protein quality control under normal and stress conditions
  Dr H Lu, Prof C M Grant, Prof S Hubbard
Application Deadline: 31 January 2020

Funding Type

PhD Type

Mitochondria are vitally important organelles within living cells and are often described as their powerhouses, as the primary energy source for all biological activities.
  (BBSRC DTP) Understanding structure and function of the mechanosensors talin and vinculin
  Dr C Ballestrem, Prof C Baldock, Dr A Roseman
Application Deadline: 31 January 2020

Funding Type

PhD Type

The ability of cells to sense biochemical and mechanical properties of their extracellular matrix (ECM) environment is critical for the development of functional tissue.
  (BBSRC DTP) Understanding the contribution of dietary extracellular vesicles to healthy human development
  Prof M Westwood, Dr L Harris, Prof A Nicolaou, Dr A Stevens
Application Deadline: 31 January 2020

Funding Type

PhD Type

The ability to adapt behaviour in response to nutrient availability is important for all cells but particularly so for trophoblasts, as these cells form the placenta - the interface between mother and fetus - and act as fetal sentinels of the maternal environment.
  (BBSRC DTP) Understanding the role of RNA binding proteins in the regulation of NF-kappa B dynamics, inflammation and cell death
  Prof M White, Dr A P Gilmore, Prof S Griffiths-Jones, Dr M Muldoon
Application Deadline: 31 January 2020

Funding Type

PhD Type

NF-kB is a key signalling system that controls inflammation and cell fate, dysregulation of which can lead to inflammatory disease or cancer.
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