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University of Bradford, Faculty of Life Sciences PhD Projects, Programs & Scholarships

We have 45 University of Bradford, Faculty of Life Sciences PhD Projects, Programs & Scholarships

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Faculty of Life Sciences  University of Bradford

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We have 45 University of Bradford, Faculty of Life Sciences PhD Projects, Programs & Scholarships

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Design, synthesis and evaluation of new integrin-targeting drugs

  Research Group: Institute of Cancer Therapeutics
The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Healthcare Degrees: What are the key drivers and influencers in choosing a healthcare career?

  Research Group: Education Innovation Research and Development
This project will investigate the current factors that influence applicants’ decisions to study for a healthcare degree and pursue a vocational career. Read more

How effective is 3D reconstructed human skin as an alternative to human skin for permeation studies?

  Research Group: Medicines Development and Pharmaceutical Sciences
The assessment of percutaneous absorption of molecules is a very important step in the evaluation of any transdermal drug delivery system. Read more

Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Computational Design of Multimodal Nanoparticle Components

  Research Group: Chemistry and Biosciences
The aim of this PhD project is to use computational methods to study conjugated polymers, conjugated polyelectrolytes (CP/CPEs) and aggregation induced emission (AIE) fluorogens for medical applications which, when in an experimental setting, should be able to simultaneously demonstrate capabilities of fluorescence imaging, photoacoustic (PA) imaging and photothermal (PT) therapy. Read more

Central role of the adipokine chemerin in energy balance regulation and neuroinflammation

  Research Group: Chemistry and Biosciences
Multiple factors related to modern lifestyle, such as sedentary behaviour and overconsumption calorie-dense foods disrupt energy homeostasis and facilitate weight gain. Read more

Understanding skin ageing using a vascularised human skin equivalent model

The main purpose of this project is to develop a skin equivalent model that incorporates microvasculature, which will then be used to address several important questions in the area of skin ageing. Read more

Pharmaceutical cocrystallisation for improved medicines

  Research Group: Centre for Pharmaceutical Engineering Science
Active pharmaceutical ingredients (APIs) are frequently delivered to the patients in the solid-state formulation. Numerous tons of tablets are produced daily worldwide by pharmaceutical industry. Read more

Aldehyde dehydrogenase expression and function in cancer stem cells

  Research Group: Institute of Cancer Therapeutics
Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction. Read more

Biological rhythms and the dopamine system in cognitive dysfunction

  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

Health Opportunity for Patient Empowerment in Gestational Diabetes (HOPE-GDM)

  Research Group: Chemistry and Biosciences
Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy. Read more

Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

  Research Group: Pharmacology and Experimental Therapeutics
Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

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