We have 44 University of Bradford, Faculty of Life Sciences PhD Projects, Programmes & Scholarships

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Faculty of Life Sciences  University of Bradford

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University of Bradford, Faculty of Life Sciences PhD Projects, Programmes & Scholarships

We have 44 University of Bradford, Faculty of Life Sciences PhD Projects, Programmes & Scholarships

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more

Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

The role of vitamin D3 in treating skin cancer and preventing drug resistance

  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more

The role of ageing cutaneous fibroblasts in modulating melanocyte pigmentation

  Research Group: Centre for Skin Sciences
The aim of the project is to gain an understanding of how aged skin fibroblasts and their secretory phenotype contribute to ageing pigmentation and commonly associated disorders. Read more

Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Rational Control of Crystal Morphology

  Research Group: Chemistry and Biosciences
The external shape of crystalline particles (called morphology) is of paramount importance in a wide range of applications, in particular pharmaceuticals and pigments. Read more

Polysialyltransferases as a target in metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Pathways to a healthy lifespan: investigating the exceptional fertility of Naked Mole Rats

  Research Group: Chemistry and Biosciences
As women age, their reproductive system undertakes significant changes that impact on their fertility and overall health. Despite its importance to society, research that could delay or limit these impacts on women’s health is held back by a lack of suitable models. Read more

Oxidic Nanomaterials for High Density Storage in Li-ion Batteries

  Research Group: Chemistry and Biosciences
The oxides of a number of materials are very appealing candidates as substitutes for conventional anodes in lithium-ion batteries because of their high theoretical capacity, high electric conductivity low potential of lithium ion intercalation, as well as superior electron mobilities, with one such material, SnO2 being particularly appealing. Read more

Novel strategy for treatment of chronic wounds via multi-functional liposomal nanocarriers

  Research Group: Medicines Development and Pharmaceutical Sciences
A confounding issue of non-healing skin wounds is the presence of pathogenic bacteria, that protect themselves from conventional antibiotic treatments by encasing themselves within protective shields (biofilms). Read more

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