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We have 46 University of Bradford, Faculty of Life Sciences PhD Projects, Programmes & Scholarships

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University of Bradford, Faculty of Life Sciences PhD Projects, Programmes & Scholarships

We have 46 University of Bradford, Faculty of Life Sciences PhD Projects, Programmes & Scholarships

University of Bradford

Making Knowledge Work at the University of Bradford

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more
 Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using Exposome, Omics, and AI to Develop a Digital Platform for Tailoring the Care of Children with Autism Spectrum Disorders

University of Bradford Faculty of Life Sciences
Autism spectrum disorders (ASD) are characterized by social impairments, repetitive behaviours, and restricted interests [1]. Over the past 20 years, there is a significant increase in the incidence of Autism spectrum disorders in the UK [1]. Read more
 Supervisors: Dr S Morsy, Dr M Elshehaly, Prof C Wright
 22 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
 Supervisors: Dr J Muller, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more
 Supervisor: Dr Muhammad Wahajuddin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more
 Supervisors: Dr M Hussain, Dr C Willis, Prof MR Boyett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more
 Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Beat-to-beat modulation of Calcium-induced Calcium release in cardiac muscle

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
Contraction in the heart is well known to be dependent on a transient rise in intracellular calcium concentration. Read more
 Supervisors: Dr M Hussain, Dr J Muller, Prof MR Boyett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
 Supervisors: Dr T Nasim, Prof C Wright
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more
 Supervisors: Dr T Nasim, Dr M Najafzadeh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more
 Supervisor: Dr T Nasim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of vitamin D3 in treating skin cancer and preventing drug resistance

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more
 Supervisors: Dr M Sutherland, Dr H Sheldrake, Dr S Kauser
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of ageing cutaneous fibroblasts in modulating melanocyte pigmentation

University of Bradford Faculty of Life Sciences
  Research Group: Centre for Skin Sciences
The aim of the project is to gain an understanding of how aged skin fibroblasts and their secretory phenotype contribute to ageing pigmentation and commonly associated disorders. Read more
 Supervisors: Dr S Kauser, Dr S Sikkink, Dr F Sefat
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Rational Control of Crystal Morphology

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
The external shape of crystalline particles (called morphology) is of paramount importance in a wide range of applications, in particular pharmaceuticals and pigments. Read more
 Supervisor: Dr C Seaton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Pathways to a healthy lifespan: investigating the exceptional fertility of Naked Mole Rats

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
As women age, their reproductive system undertakes significant changes that impact on their fertility and overall health. Despite its importance to society, research that could delay or limit these impacts on women’s health is held back by a lack of suitable models. Read more
 Supervisors: Dr P Nicholls, Dr G Helfer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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