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The University of Manchester General (Biological & Medical Sciences) PhD Projects, Programs & Scholarships

We have 17 The University of Manchester General (Biological & Medical Sciences) PhD Projects, Programs & Scholarships

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The University of Manchester

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We have 17 The University of Manchester General (Biological & Medical Sciences) PhD Projects, Programs & Scholarships

Exploiting ERK5-signalling to modify T-cell behaviour during tumour progression and radiotherapy response: a new immunotherapy approach?

T-cells can attack tumours (so called anti-tumour responses), causing a reduction in tumour size or even elimination of the tumour. However, in many tumours the tumour “switches off” anti-tumour T-cell responses. Several immunotherapy drugs have been developed that switch anti-tumour T-cell responses back on in patients. Read more

Proteomic biomarkers for disease progression in SARS-CoV-2 infections

SARS-CoV-2 is a coronavirus to which we apparently have no immunity and presents a challenge for humankind across the world. The proposed project is to identify molecular markers for Covid-19 disease progression. Read more

Acceptability, validation and extension of a novel digital manikin for identifying location and intensity of pain

Pain is a common symptom of all musculoskeletal diseases, and prominent in many other conditions, such as cancer. It substantially affects people’s quality of life and imposes a significant burden on society due to treatment costs and absence from work. Read more

The role of Myh10 (Non-Muscle Myosin IIB) in epicardial-myocardial cross talk during coronary vessel development.

During cardiac development the coronary vessels form from the epicardium, which is the outer epithelial cell layer of the heart. Formation of the coronary vasculature is a critical event in cardiac development, since the vasculature is required to nourish the cardiac muscle and maintain cardiac function throughout life. Read more

Immune phenotyping of refractory rheumatoid arthritis disease

Treatment of rheumatoid arthritis (RA) has been transformed with the introduction of targeted therapies twenty years ago (comprising biologic disease modifying anti-rheumatic drugs, bDMARDS; and the more recent small molecule JAK inhibitors). Read more

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