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Genetics (cell culture) PhD Projects, Programs & Scholarships

We have 85 Genetics (cell culture) PhD Projects, Programs & Scholarships

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  Mechanistic analysis of neurodevelopmental disorders caused by mutations in the gene RAC1
  Dr T Millard, Dr S Banka
Applications accepted all year round

Funding Type

PhD Type

RAC1 is a signalling protein that regulates many cellular processes and is essential during embryonic development. We recently discovered a novel genetic disease called RAC1-related neurodevelopmental disorder (RRND) that results from mutations in the RAC1 gene.
  Species-specific remodelling of host cells in the most pathogenic malaria causing parasite Plasmodium falciparum
  Dr M Treeck
Application Deadline: 23 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Moritz Treeckā€™s Group based at the Francis Crick Institute (the Crick). The most severe form of human malaria is caused by the parasite Plasmodium falciparum.
  The role of extracellular vesicles and glycosylation in breast cancer metastasis
  Prof D Carter, Prof S Brooks
Application Deadline: 31 December 2019

Funding Type

PhD Type

Oxford Brookes University. Faculty of Health and Life Sciences,. Department of Biomedical and Medical Sciences. 3 Year, full-time PhD studentship.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
  Generation of transplant tissue following correction of patient stem cells by genomic engineering
  Dr F Manson, Dr RL Taylor, Dr A Adamson
Applications accepted all year round

Funding Type

PhD Type

A number of retinal degenerations result from mutations in genes expressed in the retinal pigment epithelium (RPE) which lies under the photoreceptors.
  GW4 BioMed MRC DTP studentship: The epigenetic network mediated by Ehmt1 and its role in neurodevelopment disorders (NDD)
  Prof A Harwood
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project investigates how the epigenetic regulator EHMT1 controls the gene regulatory network that underlies human neurodevelopment, and how its dysfunction leads to Kleefstra Syndrome (KS) and increased risk for schizophrenia.
  (MRC DTP) RAC1 mutations in human neurodevelopmental syndrome: from mechanism to treatment
  Dr T Millard, Dr S Banka, Dr S Woolner, Prof V Allan
Application Deadline: 15 November 2019

Funding Type

PhD Type

RAC1 regulates a variety of essential cellular functions1,2,3. We recently showed that it is critical for normal human development by discovering a novel neurodevelopmental syndrome caused by mutations in the RAC1 gene4.
  Characterising protective local and systemic immune responses to Group A streptococcal throat infection in children
  Prof A Finn, Dr L B Nicholson
Application Deadline: 25 November 2019

Funding Type

PhD Type

The project. Group A streptococcus (GAS) causes infective, invasive and post-infective immune-mediated diseases including serious heart and kidney conditions resulting in significant illness and 0.5-1.5 million deaths/year globally.
  *EASTBIO* How does a mammalian cell physically organise the complex processes of gene expression and regulation?
  Research Group: Biomedical Sciences Research Centre
  Dr J Sleeman
Application Deadline: 5 January 2020

Funding Type

PhD Type

BBSRC Thematic Group. Frontier Bioscience. Accurate gene expression and regulation in mammalian cells is a hugely complex process, essential for cellular and organismal homeostasis.
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