Genetics (data) PhD Projects, Programmes & Scholarships

We have 108 Genetics (data) PhD Projects, Programmes & Scholarships

Health outcomes of children with rare or complex conditions and their families: a longitudinal cohort study using linked primary and secondary healthcare data in England

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

Rare or complex conditions (RCCs), such as major congenital anomalies or inherited conditions that are screened for in newborns, have serious health, functional and social consequences for affected individuals. Read more

Supervisors: Dr AZ Zylbersztejn, Dr J Tan, Prof MCB Cortina Borja

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Multimodal Artificial Intelligence for the Detection and stratification of Necrotising Enterocolitis in premature born infants (MAIDNEC)

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

Necrotising Enterocolitis (NEC) is a severe gastrointestinal inflammatory condition affecting neonates, most commonly premature infants although up to 25% is observed among full-term babies1. Read more

Supervisors: Dr S Eaton, Dr E Mazomenos

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Mining data from National genomics Research Library to enable new gene discovery

University of Sheffield School of Medicine and Population Health

Whole Genome Sequencing (WGS) is a new genomic testing technology and process which became available through the NHS in April 2022. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Estimating the global cancer burden due to low levels of physical activity

University of Bristol Bristol Medical School

Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more

Supervisors: Dr S Lewis, Prof R Martin, Dr R Pulsford, Prof R Jago, Dr FB Bray

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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The use of life course epidemiology to support the experimental characterisation of genetic variation

University of Bristol Bristol Medical School

Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more

Supervisors: Prof N Timpson, Dr L Corbin, Dr BL Lam

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 12%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more

Supervisor: Prof E Costello

23 May 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic architecture of orofacial cleft: A genome-wide association study using trio data and an investigation of parent of origin and mother-children interaction effects.

University of Bristol Bristol Medical School

Rationale. Orofacial clefts (OFCs) are the most prevalent craniofacial congenital disabilities globally, occurring at a frequency of 1 out of 700 newborns. Read more

Supervisors: Dr S Lewis, Dr E Stergiakouli, Prof H Cordell

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Delineating the IRF6 regulatory network driving periderm formation and function

The University of Manchester Faculty of Biology, Medicine and Health

During development, the ectoderm passes through a series of cell states to produce a self-replenishing, multi-layered epidermis. Initial stratification forms a single-cell layer of flattened periderm cells which act as a barrier to prevent pathological adhesions during embryogenesis. Read more

Supervisors: Prof M Dixon, Dr J Dixon

Year round applications PhD Research Project Self-Funded PhD Students Only

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Application of machine learning algorithms to medical images and clinical/DNA data

The University of Manchester Department of Electronic and Electrical Engineering

This project will develop an automated classifier or the estimation of prognosis of the illness using medical images of the human body, clinical data, and gene information. Read more

Supervisor: Dr F Costen

Year round applications PhD Research Project Self-Funded PhD Students Only

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Determining the biological basis of observed clinical outcomes in juvenile idiopathic arthritis using genetics and multiomics

The University of Manchester Faculty of Biology, Medicine and Health

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis affecting children and young people with an age of disease onset less than 16 years of age. Read more

Supervisors: Dr J Bowes, Dr J Humphreys

Year round applications PhD Research Project Self-Funded PhD Students Only

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Common genetic origins of visual and neurocognitive disorders

University of York York Biomedical Research Institute

There is emerging evidence that apparently distinct neurodegenerative diseases have common genetic origins. For example, genes such as ARMS2 and HTRA1, which are fundamental to regulating neuronal health, are implicated in both dementia and diseases of the retina (particularly age-related macular degeneration). Read more

Supervisors: Prof A Wade, Prof A Morland, Dr H Baseler

Year round applications PhD Research Project Self-Funded PhD Students Only

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The Role of Nutrition and Exercise in Physical and Cognitive Function (such as sarcopenia and frailty), utilizing clinical, metabolomic, proteomic, and gut microbiota data

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty is a result of hallmarks of aging, where gut microbiome (GM) dysbiosis and dietary pattern play a significant role. Read more

Supervisor: Dr M Isanejad

Year round applications PhD Research Project Self-Funded PhD Students Only

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Health and development outcomes and their interaction for children with chronic liver disease: a population-based cohort using novel linkage between health and education records

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

Each year in the UK, 400 children are diagnosed with chronic liver disease (CLD), with a fifth requiring liver transplantation at some stage. Read more

Supervisors: Prof KH Harron, Dr AZ Zylbersztejn

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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AI-assisted diagnosis, surgical planning & implant design for craniofacial patient care

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Craniofacial diseases, particularly in craniosynostosis cases, present significant challenges in diagnosis and treatment. Read more

Supervisors: Dr S Schievano, Prof O Jeelani

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 108 Genetics (data) PhD Projects, Programmes & Scholarships

Genetics (data) PhD Projects, Programmes & Scholarships

We have 108 Genetics (data) PhD Projects, Programmes & Scholarships

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