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Genetics (genetic manipulation) PhD Projects, Programs & Scholarships

We have 21 Genetics (genetic manipulation) PhD Projects, Programs & Scholarships

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We have 21 Genetics (genetic manipulation) PhD Projects, Programs & Scholarships

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Finding new antibiotics in the soil microbiota (MALONE_J22MMB)

The increase in drug-resistant bacterial infections is a major global health threat. This crisis is exacerbated by a lack of new antibiotics, caused by multiple factors including the frequent rediscovery of known antibiotics. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Understanding complement system dysregulation in the tumour microenvironment

Inducing a stress response analogous to anti-viral immunity is important for maximising immune responses against the tumour. However, tumours evolve evasion strategies that can limit these responses. Read more

Genetic manipulations in bats: using transgenic bats to understand vocal learning and language

  Research Group: Centre for Biological Diversity
In speech acquisition, humans must employ vocal learning, making this a key trait for the understanding of the biology and evolution of speech and language. Read more

Stem Cells: Developing pluripotent stem cell models of inherited retinal diseases

Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide. Read more

CRISPR manipulation of gene expression in retinal organoids to model and rescue human disease

Human pluripotent stem cells can be used in the lab to grow 3D retinal structures called retinal organoids. This allows us to investigate both the early and later events of human eye development and disease. Read more

What is the role of intestinal mucins in health maintenance during ageing?

An increasing proportion of our population falls within the elderly age bracket. As a result, the identification of interventions that help people stay healthy into their old age is one of the most significant challenges facing biomedical research. Read more

Understanding the molecular mechanisms of plant disease resistance

Plant pathogens pose major challenges both to crop production and to the resilience of natural ecosystems. How we protect plants from their most damaging pathogens is therefore vital to a future of sustainable agriculture and forestry. Read more

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