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We have 31 Genetics (in vitro) PhD Projects, Programmes & Scholarships

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Genetics (in vitro) PhD Projects, Programmes & Scholarships

We have 31 Genetics (in vitro) PhD Projects, Programmes & Scholarships

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The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

The University of Manchester Faculty of Biology, Medicine and Health
Infections caused by Aspergillus fumigatus (Af) cause more deaths globally than any other fungal disease. Over 20 million are affected annually with four million having life threatening invasive and chronic infections with high morbidity and mortality up to 90%. Read more
 Supervisors: Dr N.V.R Van Rhijn, Dr M Bromley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Competition and cooperation relationships within human microbial communities.

University of Nottingham School of Life Sciences
Typical studies of the human microbiome identify dysbiosis by sampling from healthy individuals, comparing them to individuals with a particular disease state, and reporting changes in the presence and/or abundance of bacterial species. Read more
 Supervisors: Dr F Whelan, Dr K Hardie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Vascularising human mini-brains in a dish

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Blood vessels play a pivotal role in brain development and function. They promote tissue growth and survival by supplying nutrients and oxygen to surrounding tissues, signals to progenitor populations, as well as guiding neuronal migration. Read more
 Supervisors: Dr PA Alexandre, Prof D Long
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Developing therapies targeting inflammation and dysfunctional matrix biology in neurological and ocular disease

University of Birmingham School of Biomedical Sciences
We are seeking talented, motivated students with a passion for research in inflammation and matrix biology in the eye and brain to join our team co-led by Dr Lisa Hill https://www.birmingham.ac.uk/staff/profiles/clinical-sciences/hill-lisa.aspx and Dr Hannah Botfield https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/botfield-hannah.aspx. Read more
 Supervisors: Dr H B Botfield , Dr L Hill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How to build and maintain a 3-dimensional polarised epithelial sheet

University of Nottingham School of Life Sciences
We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more
 Supervisor: Dr M Georgiou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more
 Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition

University of Reading Department of Biomedical Sciences
Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more
 Supervisor: Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

King’s College London School of Cancer and Pharmaceutical Sciences
Talented and motivated students, passionate about doing research and advancing cancer research, are invited to apply for this PhD position. Read more
 Supervisor: Dr H Sailem
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences
The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more
 Supervisor: Dr B Poulet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The use of life course epidemiology to support the experimental characterisation of genetic variation

University of Bristol Bristol Medical School
Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more
 Supervisors: Prof N Timpson, Dr L Corbin, Dr BL Lam
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

University of Bristol Bristol Medical School
Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more
 Supervisor: Prof S Satchell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Chromatin remodelling complexes in human brain development

King’s College London Faculty of Life Sciences & Medicine
Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more
 Supervisors: Dr CD Dias, Dr JA Atherton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute
Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more
 Supervisors: Dr M Secrier, Dr L Cottone
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Investigating lysosomal (dys)function in ageing and neurodegeneration

University of Reading Department of Biomedical Sciences
Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more
 Supervisors: Dr S Cogo, Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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