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We have 79 Genetics (model) PhD Projects, Programmes & Scholarships

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Genetics (model) PhD Projects, Programmes & Scholarships

We have 79 Genetics (model) PhD Projects, Programmes & Scholarships

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more
 Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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How does early life influence the brain and behavioural profile of a mouse model for schizophrenia

Cardiff University Cardiff School of Medicine
Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more
 Supervisor: Prof A R Isles
 7 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health
Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more
 Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: From GWAS to causative genes

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr A Lionikas, Dr B Gabriel
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating monogenic disorders of the protein synthesis machinery

The University of Manchester Faculty of Biology, Medicine and Health
Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more
 Supervisors: Dr P Kasher, Dr S Banka, Prof G D Pavitt
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Somatic evolution in plants

Anglia Ruskin University ARU School of Life Sciences
Fixed term contract for 3 years, commencing September 2024. Bursary of £19,237 per annum and a full fee-waiver for UK tuition fees. Read more
 Supervisor: Dr M Carter-Brown
 31 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Early life environment changes how organisms age.

University of Leicester Department of Genetics and Genome Biology
This project will help understand why organisms age differently by establishing the effect of early life environments on epigenetic ageing in the model insect, Nasonia vitripennis. Read more
 Supervisor: Prof E Mallon
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unravelling the role of P4HB in skeletal development: towards treatment of heritable bone fragility

University of Sheffield School of Medicine and Population Health
Osteogenesis Imperfecta (OI) affects 1 in 15-20,000 live births and results in a childhood with frequent fractures, reduced mobility and joint problems. Read more
 Supervisor: Dr M Balasubramanian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr SA Ahmed, Dr NP Peake, Dr DK Kelly
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition

University of Reading Department of Biomedical Sciences
Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more
 Supervisor: Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidating the mechanisms of pathology in neurodevelopmental white matter diseases

University of York York Biomedical Research Institute
Our research interests are to dissect the mechanism of auto-inflammatory neurological disorders using zebrafish as an animal model. Read more
 Supervisors: Dr N Hamilton, Dr S Sweeney
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A deep-learning approach to genomic regulation of tissue-specific alternative splicing

The University of Manchester Faculty of Biology, Medicine and Health
Each human gene is a blueprint for multiple distinct RNA transcripts that can be produced in differing quantities based on the localisation of the transcribing… Read more
 Supervisors: Dr JE Eales, Prof T Papamarkou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding Spinal Cord Regeneration: The role of dynamic gene expression

The University of Manchester Faculty of Biology, Medicine and Health
Spinal cord injury(SCI) paralysis is a devastating disease that affects at least 2500 people per year in the UK. It carries substantial individual and societal costs with most SCI sufferers experiencing chronic pain. Read more
 Supervisors: Dr X Soto Rodriguez, Dr K Dorey, Dr Cerys Manning
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more
 Supervisors: Dr G Galea, Prof J Sowden
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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