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We have 28 Genetics (molecular interactions) PhD Projects, Programmes & Scholarships

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Genetics (molecular interactions) PhD Projects, Programmes & Scholarships

We have 28 Genetics (molecular interactions) PhD Projects, Programmes & Scholarships

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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School
Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more
 Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigation of host-virus interactions

University of Leeds Faculty of Biological Sciences
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25 in the area of molecular virology. Read more
 Supervisors: Dr M Stacey, Dr J N Barr
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Epilepsy Molecular Mechanisms in Patient-Specific Stem Cell Models of SLC6A1 Deficiency

Newcastle University Faculty of Medical Sciences Graduate School
SLC6A1 encodes GAT-1, a voltage-dependent gamma-aminobutyric acid (GABA) transporter that is responsible for the reuptake of GABA from the synapse. Read more
 Supervisors: Dr M Alsaqati, Prof A Trevelyan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Speeding up the plant microbiota: investigating the impact of speed breeding on host-microbe interactions in the barley rhizosphere

University of Dundee School of Life Sciences
Feeding a growing world population amid climatic modifications and international conflicts represents an unprecedent challenge for crop production. Read more
 Supervisors: Dr D Bulgarelli, Dr C Campoli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bioinformatics studies of protein structures, functions and their interactions

University of Reading Department of Biomedical Sciences
The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease. Read more
 Supervisor: Prof L J McGuffin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more
 Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Molecular characterisation of scavenger receptor ligand binding.

University of Sheffield School of Biosciences
Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more
 Supervisors: Dr S Brown, Dr I Evans
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the genetic architecture of orofacial cleft: A genome-wide association study using trio data and an investigation of parent of origin and mother-children interaction effects.

University of Bristol Bristol Medical School
Rationale. Orofacial clefts (OFCs) are the most prevalent craniofacial congenital disabilities globally, occurring at a frequency of 1 out of 700 newborns. Read more
 Supervisors: Dr S Lewis, Dr E Stergiakouli, Prof H Cordell
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll, Dr GL Leyden
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Chromatin remodelling complexes in human brain development

King’s College London Faculty of Life Sciences & Medicine
Chromatin regulators are a group of proteins that control the way the rest of the genome is opened up and “read” by the cellular machinery, with fundamental roles in development and disease. Read more
 Supervisors: Dr CD Dias, Dr JA Atherton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Probing Death Decisions from Morphogen Gradient Fields

University of Liverpool Department of Molecular and Clinical Cancer Medicine
Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more
 Supervisor: Dr MM Merino
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley

University of Dundee School of Life Sciences
Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied. Read more
 Supervisor: Prof C Halpin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biophysical explorations of neural crest cell behaviours in development and cancer

King’s College London School of Natural & Mathematical Sciences
Neural crest cells are highly migratory. These cells travel throughout the developing embryo, eventually contributing to most organ systems, including the peripheral nervous system, pigment cells and craniofacial skeleton. Read more
 Supervisors: Prof R Isaacson, Prof K Liu
 10 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more
 Supervisor: Dr M Soller
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Identifying causal pathways to disease using DNA methylation predicted blood traits.

University of Bristol Bristol Medical School
Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more
 Supervisors: Dr J Min, Dr E Hannon, Prof J MIll
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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