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Genetics (signal) PhD Projects, Programs & Scholarships

We have 10 Genetics (signal) PhD Projects, Programs & Scholarships

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  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
  Clustering in bioinformatics
  Prof AK Nandi
Applications accepted all year round

Funding Type

PhD Type

There are many bioinformatics datasets available publically. Extracting consistent information from these require development of novel techniques and tools.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  The functions of the Class II Pi3-kinase signals in vivo
  Dr L MacDougall, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies.
  Understanding mechanisms of Notch regulation and misregulation in endocytic pathway
  Dr M Baron, Dr R Clarke
Applications accepted all year round

Funding Type

PhD Type

Notch is a developmental signalling receptor with widespread and important roles in metazoan development and also in adult stem cell regulation.
  Build and destroy: investigating targeted protein degradation in plant development and stress-response
  Dr D Gibbs
Applications accepted all year round

Funding Type

PhD Type

In order to effectively co-ordinate their growth and development, plants need to be able to respond to changes in their environment, whether it is adapting to the seasons or coping with stresses.
  Alpha-defensin haplotypes and IgA nephropathy risk
  Prof J A L Armour, Prof O Hanotte
Applications accepted all year round

Funding Type

PhD Type

The human alpha-defensin genes DEFA1 and DEFA3 encode short antimicrobial peptides that are important components of the innate immune system, and are subject to copy number variation (CNV) with individuals having between 3 and 18 copies.
  Photoreceptor regulation of plant development
  Dr S Casson
Applications accepted all year round

Funding Type

PhD Type

Plant growth and development is highly dependent on the light environment. Light provides energy to drive photosynthesis but light quality and quantity is also perceived by photoreceptors, which signal to regulate responses enabling plants to adapt to their environment.
  The Role of Fusion Genes Tumourigenesis
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Salivary gland tumours are uncommon but have a varied and complex pattern of histopathological features.
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