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Genetics (transcription) PhD Projects, Programs & Scholarships

We have 29 Genetics (transcription) PhD Projects, Programs & Scholarships

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  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  Unveiling mechanisms of differentiation in neuroblastoma: from pathway discovery towards epigenetic-targeted drugs
  Dr O Piskareva
Application Deadline: 29 May 2020

Funding Type

PhD Type

Cell fate determination and differentiation are processes that are crucial in developmental biology, which assigns cells their functional roles and gives them a unique identity.
  Epigenetics and chromatin regulatory proteins in Drosophila
  Research Group: Mattias Mannervik
  Prof M Mannervik
Application Deadline: 23 April 2020

Funding Type

PhD Type

Epigenetics can be defined as non-genetic changes in cellular phenotype that are transmitted through cell-divisions. Epigenetic patterns of histone modifications contribute to the maintenance of cell- and tissue-specific gene expression.
  Deciphering a novel anti-ageing epigenetic programme
  Dr G Poulin, Prof A Sharrocks
Applications accepted all year round

Funding Type

PhD Type

Over two decades of intense research in the field of epigenetics have produced compelling evidence that chromatin modifications are crucial for processes such as DNA repair, transcription, splicing, mitosis, meiosis, and in the preservation of the epigenetic memory of cells.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Prof J Fallowfield
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  Precision Medicine DTP – Using Omics to Understand the Genes and Pathways Underlying Alcohol Use Disorder
  Research Group: Centre of Genomic and Experimental Medicine
  Dr K Evans, Dr T-K Clarke, Dr S Glerup
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Alcohol misuse is a huge public health problem, and those who attempt to curtail consumption can be hampered by highly aversive withdrawal symptoms.
  Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye
  Dr M Ali, Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Eye diseases are a common cause of human disability and many of them are inherited. These include congenital as well as adult-onset conditions and diseases of ageing, and may involve abnormalities at the back of the eye or the anterior eye structures.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  What is the impact of atypical neurogenesis on brain activity, cognition and behaviour?
  Dr A McNeill, Dr M Freeth
Applications accepted all year round

Funding Type

PhD Type

Neurogenesis is the process by which stem cells form brain cells. This process is disrupted by genetic mutations causing childhood neurological disorders which cause symptoms such as learning disability, behaviour problems and epilepsy.
  The Role of Fusion Genes Tumourigenesis
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Salivary gland tumours are uncommon but have a varied and complex pattern of histopathological features.
  Hormone regulation of fungal pathogenicity
  Dr R Hall
Application Deadline: 17 April 2020

Funding Type

PhD Type

Candida albicans is an commensal yeast residing in the oral, gastrointestinal and urogenital tracks in up to 80% of the population.
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