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Genetics (transcription) PhD Projects, Programs & Scholarships

We have 71 Genetics (transcription) PhD Projects, Programs & Scholarships

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  Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression
  Dr D Blažek, Assoc Prof Z Zdráhal, Dr P Alexiou
Application Deadline: 18 December 2019

Funding Type

PhD Type

CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development.
  Using statistical and functional analysis to investigate the contrasting disease specific roles of IL6R and the chr17q12 locus in the development of rheumatoid arthritis and asthma
  Dr J Curtin, Prof A Simpson
Applications accepted all year round

Funding Type

PhD Type

The Arthritis Research UK and Respiratory Centres at the University of Manchester have extensive research programmes investigating the genetic components of rheumatoid arthritis (RA) and asthma.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Protein glycosylation as a novel biomarker for bile duct cancer and other liver diseases
  Dr P-S Jayaraman
Application Deadline: 12 January 2020

Funding Type

PhD Type

Protein modifications are important in many diseases including fibrosis and cancer. In protein glycosylation carbohydrate polymers, or glycans, are covalently attached to proteins forming glycoproteins.
  Build and destroy: investigating targeted protein degradation in plant development and stress-response
  Dr D Gibbs
Applications accepted all year round

Funding Type

PhD Type

In order to effectively co-ordinate their growth and development, plants need to be able to respond to changes in their environment, whether it is adapting to the seasons or coping with stresses.
  RNA metabolism in response to cellular stress
  Dr P Grzechnik, Dr S Brogna
Application Deadline: 31 January 2020

Funding Type

PhD Type

The aim of the project is to understand roles for mRNA processing during the stress response in eukaryotic cells. Exposure to acute stress reduces cell viability or fitness and therefore immediate adaption is crucial for cell survival.
  EASTBIO A quantitative approach to understanding regulation of developmental genes by bivalent promoters
  Research Group: Institute of Cell Biology
  Dr P Voigt, Dr G Sanguinetti
Application Deadline: 5 January 2020

Funding Type

PhD Type

Histone modifications play key roles in the regulation of gene expression. In embryonic stem cells, promoters of developmental genes carry a signature combination of histone H3 lysine 4 trimethylation (H3K4me3), which is usually found at active promoters, and H3K27me3, a hallmark of repressive chromatin.
  EASTBIO Defining the structural basis of Tdp1-dependent DNA repair
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr J Richardson, Dr H Interthal
Application Deadline: 5 January 2020

Funding Type

PhD Type

DNA topoisomerases are described as “magicians of the DNA world”. They allow DNA strands and double helices to “pass through each other” thereby resolving topological strain created during DNA replication and transcription.
  Plant Stem Cell formation
  Prof T Laux
Applications accepted all year round

Funding Type

PhD Type

We are seeking highly motivated candidates for a newly funded PhD position in plant embryo development. The goal is to investigate how the stem cells of the shoot meristem are formed during embryo development.
  The molecular mechanisms underlying reproductive organ photosynthesis
  Dr D O'Maoileidigh
Applications accepted all year round

Funding Type

PhD Type

Increasing crop yields while decreasing environmental impacts of agriculture is one of the major challenges facing modern society.
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