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Genetics (transgenic) PhD Projects, Programs & Scholarships

We have 18 Genetics (transgenic) PhD Projects, Programs & Scholarships

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  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  (MRC DTP) Investigating the role of neuroinflammation and cholesterol metabolism in the progression of brain injury following intracerebral haemorrhage
  Dr P Kasher, Dr D Brough, Prof S Allan, Dr A Parry-Jones
Application Deadline: 15 November 2019

Funding Type

PhD Type

Intracerebral haemorrhage (ICH) is a type of stroke caused by spontaneous bleeding within the brain.
  Egr2 and 3 mediated T cell tolerance in cancer and their impact in immune checkpoint therapy
  Dr S Li
Applications accepted all year round

Funding Type

PhD Type

Tumour infiltrated lymphocytes (TILs) contain tumour reactive T cells and have been used as adoptive cell transfer therapy in patients which can mediate cancer regression.
  Can improved genetic understanding of grain weight help feed the world? (UAUYJ20DTP)
  Dr C Uauy
Application Deadline: 25 November 2019

Funding Type

PhD Type

Wheat provides 20% of the calories and protein consumed by humans. The world population will reach 9 billion by 2050, which requires food production to more than double.
  Cellular cross-talk at the perivascular niche and the blood brain barrier
  Prof B Hogan
Applications accepted all year round

Funding Type

PhD Type

Much research on vasculature has focussed on the endothelial cells that line functional vessels, however the milieu of cells that surround vessels (mural cells) play important and under-appreciated roles in homeostasis and disease.
  The Hippo pathway and Yap1 in vascular growth control in development and disease
  Prof B Hogan, Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Lymphatic vessels play roles in the drainage of tissue fluid, trafficking of immune cells and the metastatic spread of cancer.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round

Funding Type

PhD Type

The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Interneuron Development in the Zebrafish Spinal Cord
  Dr K Lewis
Applications accepted all year round

Funding Type

PhD Type

The Lewis Lab moved to Syracuse University from Cambridge University in the UK in 2010.
  Early detection of colorectal cancer
  Dr V Li
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Vivian Li’s Group based at the Francis Crick Institute (the Crick).
  Function of miRNAs in formation and regeneration of human hair follicles
  Dr S Kurinna, Dr S Herrick, Prof R Paus
Applications accepted all year round

Funding Type

PhD Type

Recent advances in treating a severe skin condition with autologous transgenic keratinocyte cultures emphasises the importance of molecular mechanisms in selecting subpopulations of skin cells for cutaneous repair [1].
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