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Genetics (flow cytometry) PhD Projects, Programs & Scholarships

We have 16 Genetics (flow cytometry) PhD Projects, Programs & Scholarships

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Showing 1 to 15 of 16
  Analysing immune responses to metastatic ovarian tumours to identify therapeutic targets
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Investigating how ovarian tumours avoid immune responses in cancer patients
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
  Dr S Eyre, Mr P Martin, Dr AM Morris
Applications accepted all year round

Funding Type

PhD Type

Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect.
  Post-transcriptional regulation of transferrin receptor expression in Trypanosoma brucei
  Dr C Tiengwe
Applications accepted all year round

Funding Type

PhD Type

The goal of this project is to understand how. Trypanosoma brucei. controls expression of iron regulatory proteins in response to changes in intracellular iron.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round

Funding Type

PhD Type

Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
  Role of telomere attrition in cardiometabolic disease risk
  Dr J Buxton, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Common conditions such as Type 2 diabetes (T2D) and coronary artery disease (CAD) are complex disorders caused by a myriad of interacting genetic and lifestyle factors.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Therapy-induced senescence and stemness in ovarian cancer
  Prof R. Pearson, Dr K Chan
Applications accepted all year round

Funding Type

PhD Type

Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
  Development of iPSCs from patients with Urofacial Syndrome for disease modelling
  Prof S J Kimber, Prof A Woolf
Applications accepted all year round

Funding Type

PhD Type

Peripheral neuropathies (PNs) affect 2% of the general population. Somatic PNs cause locomotor and sensory deficits, while autonomic PNs cause cardiac dysrhythmias and gastrointestinal and urinary bladder dysfunction.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Prof J Fallowfield
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  Impact of diabetes on macrophage control of fungal allergic inflammation - PhD in Medical Studies (Research England DTP)
  Dr PC Cook, Prof N G Morgan
Application Deadline: 30 March 2020

Funding Type

PhD Type

Individuals with diabetes are at an increased risk of developing asthma, but the reasons behind this are unclear.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Development of a multicomponent, targeted gene delivery platform
  Dr P Moyle
Application Deadline: 1 May 2020

Funding Type

PhD Type

Gene delivery systems are important tools in biological research and offer many exciting future prospects. Delivering gene material is very difficult in practice.
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