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Genetics (human) PhD Projects, Programs & Scholarships

We have 281 Genetics (human) PhD Projects, Programs & Scholarships

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  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  De Novo Mutations and Human Disease
  Prof A Goriely, Prof A Wilkie
Application Deadline: 10 January 2020

Funding Type

PhD Type

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
  De Novo Mutations and Human Disease
  Prof A Goriely, Prof A Wilkie
Application Deadline: 10 January 2020

Funding Type

PhD Type

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
  MRC four-year PhD programme in Human Genetics, Genomics and Disease

Funding Type

PhD Type

Applications are invited from outstanding candidates to join an MRC funded 4-year multi-disciplinary PhD programme in Human Genetics, Genomics and Disease at the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  Understanding and predicting disease-associated mutations in dynamic and disordered regions of proteins
  Research Group: MRC Human Genetics Unit
  Dr J Marsh
Application Deadline: 13 December 2019

Funding Type

PhD Type

Applications are invited from outstanding candidates to join the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  The role of endogenous retroviruses in human health and disease
  Dr G Magiorkinis
Applications accepted all year round

Funding Type

PhD Type

More than 10 years have passed since the first high quality (nearly) complete version of the human genome and we are still exploring its functionality.
  (MRC DTP) Developing a zebrafish model for a novel human neurodevelopmental disorder
  Prof G D Pavitt, Dr P Kasher, Dr S Banka
Application Deadline: 15 November 2019

Funding Type

PhD Type

Background. We have recently discovered a novel human disorder caused by mutations in the EIF5A1 gene resulting in developmental problems, small head size and craniofacial defects in children [1].
  Precision Medicine DTP – Integration of single-cell RNA sequencing data from human and murine kidney disease to identify novel therapeutic targets
  Dr BC Conway, Dr T Chandra, Dr D Ferenbach
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease and for end-stage kidney disease (ESRD), at which point patients require dialysis or transplantation.
  Transferability of genetic risk scores for complex human diseases across diverse population groups
  Dr AM Morris, Dr J Bowes
Applications accepted all year round

Funding Type

PhD Type

Genome-wide association studies (GWAS) have been extremely successful in identifying DNA variants that are associated with a wide range of complex human traits and common diseases.
  EASTBIO: Application of MinION Nanopore sequencing to understand the impact of environmental changes on sentinel indicators of ecosystem health
  Dr E Watson
Application Deadline: 5 January 2020

Funding Type

PhD Type

We are increasingly aware that human, veterinary and environmental health is intricately linked and farming and food production systems must not only be resilient to environmental changes and threats but the systems themselves must also perform with minimal environmental impact.
  Genomics, bioinformatics and evolution of inherited chromosomal integrated human herpesvirus 6.
  Dr A Aswad, Prof B Kaufer
Applications accepted all year round

Funding Type

PhD Type

We are inviting applications for a 3-4 year PhD student in the area of bioinformatics and evolutionary genomics of endogenous Human Herpesvirus 6 (HHV-6).
  Computational methods to explore the relationship between gut microbes, metabolites and human health
  Research Group: Twin Research & Genetic Epidemiology
  Dr C Menni, Assoc Prof A Valdes
Applications accepted all year round

Funding Type

PhD Type

Start date. 1st January 2020. Metabolomics and the gut microbiome are intricately involved in susceptibility and potentially monitoring of metabolic diseases.
  (MRC DTP) RAC1 mutations in human neurodevelopmental syndrome: from mechanism to treatment
  Dr T Millard, Dr S Banka, Dr S Woolner, Prof V Allan
Application Deadline: 15 November 2019

Funding Type

PhD Type

RAC1 regulates a variety of essential cellular functions1,2,3. We recently showed that it is critical for normal human development by discovering a novel neurodevelopmental syndrome caused by mutations in the RAC1 gene4.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  SWBio DTP PhD project: Investigating conserved long non-coding RNA functions during melanocyte development in zebrafish and human melanoma
  Dr K Vance, Prof R N Kelsh
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
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