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Genetics (processing) PhD Projects, Programs & Scholarships

We have 46 Genetics (processing) PhD Projects, Programs & Scholarships

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  EASTBIO: Recurrent evolution of a eukaryotic molecular trait: acquisition of polycistronic RNA processing.
  Dr J Pettitt, Dr B Mueller, Dr M Wenzel, Prof I Stansfield
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Dr Jonathan Pettitt (University of Aberdeen). https://www.aberdeenwormlab.org/. Dr Berndt Mueller (University of Aberdeen).
  Understanding the role that the RNA helicase UPF1 plays in sorting ribonucleoprotein (RNP) complexes and the mechanism by which this role of UPF1 might reduce cellular stress and cell degeneration.
  Research Group: BBSRC MIBTP
  Dr S Brogna
Application Deadline: 7 January 2020

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  Role of metal resistance in foodborne bacterial disease
  Dr J Morrissey, Prof J M Ketley
Application Deadline: 12 January 2020

Funding Type

PhD Type

Foodborne infectious diseases are frequent and growing public health problems worldwide (World Health Organisation).
  Discovery and modelling of common molecular mechanisms disrupting hearing in genetic mutations associated with hearing loss
  Prof I D Forsythe, Dr A Lecchini-Visintini
Application Deadline: 12 January 2020

Funding Type

PhD Type

Objectives. Determine the cellular and molecular changes in the auditory brainstem of mice carrying genetic mutations associated with hearing loss and language development and use modelling to evaluate common mechanisms.
  RNA metabolism in response to cellular stress
  Dr P Grzechnik, Dr S Brogna
Application Deadline: 31 January 2020

Funding Type

PhD Type

The aim of the project is to understand roles for mRNA processing during the stress response in eukaryotic cells. Exposure to acute stress reduces cell viability or fitness and therefore immediate adaption is crucial for cell survival.
  Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression
  Dr D Blažek, Assoc Prof Z Zdráhal, Dr P Alexiou
Application Deadline: 18 December 2019

Funding Type

PhD Type

CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development.
  Regulation of mitochondrial gene expression (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Dr M Minczuk
Application Deadline: 30 June 2020

Funding Type

PhD Type

MRC Mitochondrial Biology Unit. The key objective of this PhD project is to study nuclear-encoded proteins involved in mitochondrial (mt-) RNA metabolism, in order to understand how their dysfunction is linked to human mitochondrial pathologies.
  BBSRC MIBTP: Transcriptional regulators of gene expression in human cells
  Dr P Grzechnik, Dr S Brogna
Application Deadline: 12 January 2020

Funding Type

PhD Type

Position for a PhD student is available in the group of Dr Pawel Grzechnik at the University of Birmingham. The aim of the project is to uncover novel roles for transcriptional factors and to investigate how mRNA processing alters gene expression in human cells.
  Understanding protein impact on soft wheat flour functionality: identification of protein markers for soft wheat breeding.
  Dr P Tosi, Prof D O'Sullivan
Applications accepted all year round

Funding Type

PhD Type

This is a fantastic opportunity to work at pre-breeding of soft wheat, specifically targeting its processing quality for the bakery sector.
  Understanding protein impact on soft wheat flour functionality: identification of protein markers for soft wheat breeding.
  Dr P Tosi, Prof D O'Sullivan
Applications accepted all year round

Funding Type

PhD Type

This is a fantastic opportunity to work at pre-breeding of soft wheat, specifically targeting its processing quality for the bakery sector.
  Learning from the past to predict and reduce the risk of infectious disease pandemics
  Dr F Perez-Reche, Prof N Strachan
Applications accepted all year round

Funding Type

PhD Type

The World Health Organisation reports that infectious diseases cause 63% of childhood deaths and 48% of premature deaths. There is the ongoing risk of epidemics and pandemics that can cause widespread morbidity and mortality (Spanish flu, ebola, SARS, E.
  EASTBIO: Functional genomics for understanding behaviour and learning in a single-celled brainless blob, the slime mould Physarum polycephalum
  Dr M Wenzel, Prof D Lusseau, Prof P Schaap
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Dr Marius Wenzel (University of Aberdeen). https://www.abdn.ac.uk/people/marius.wenzel. Professor David Lusseau (University of Aberdeen).
  Using CRISPR genome editing to determine the effects of obesity and hypertension associated polymorphisms
  Dr A MacKenzie, Prof M Delibegovic
Applications accepted all year round

Funding Type

PhD Type

Introduction. There is now little doubt that morbid conditions such as obesity, cardiovascular disease and diabetes are mechanistically linked.
  The impact of mixed radiation and chemicals exposure on neuronal cytotoxicity, ageing and transcription
  Dr R Anderson
Application Deadline: 6 January 2020

Funding Type

PhD Type

A 3-year funded PhD studentship is available in the College of Health and Life Sciences at Brunel University London. Project description.
  EMBLA Project - The regulation of phase transition by alternative splicing
  Dr R Weatheritt
Applications accepted all year round

Funding Type

PhD Type

More than 90% of human genes undergo alternative splicing, the process by which multiple, distinct transcript and protein variants are expressed from a single gene.
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