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We have 23 Genetics (transcription) PhD Projects, Programmes & Scholarships

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Genetics (transcription) PhD Projects, Programmes & Scholarships

We have 23 Genetics (transcription) PhD Projects, Programmes & Scholarships

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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more
 Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more
 Supervisor: Dr NB Benabdallah
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health
Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more
 Supervisor: Prof U Klein
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PhD studentship - Defining the mechanisms underpinning HIF-1 and HIF-2 dependent transcriptional specificity in hypoxia.

Newcastle University Biosciences Institute
Award summary. 100% of home tuition fees paid and annual living expenses of £18,622. Overview. The cellular response to low oxygen levels (hypoxia), is crucial for cell survival and identity. Read more
 Supervisor: Dr B Ortmann
 14 June 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The University of Manchester Faculty of Biology, Medicine and Health
The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more
 Supervisors: Dr M Lagator, Prof M Rattray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Delineating the IRF6 regulatory network driving periderm formation and function

The University of Manchester Faculty of Biology, Medicine and Health
During development, the ectoderm passes through a series of cell states to produce a self-replenishing, multi-layered epidermis. Initial stratification forms a single-cell layer of flattened periderm cells which act as a barrier to prevent pathological adhesions during embryogenesis. Read more
 Supervisors: Prof M Dixon, Dr J Dixon
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

University of Leicester Department of Genetics and Genome Biology
General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more
 Supervisors: Dr B Warren, Dr E Rosato, Dr R Feuda
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Dissecting mechanisms that control adult stem cells in health, disease, and ageing

University of Birmingham Institute of Cancer and Genomic Sciences
Research interests/description of main research theme. Read more
 Supervisors: Dr M Clarke, Prof J Frampton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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BARIToNE: Improving barley climate resilience using a candidate gene approach (Project code 24H)

The James Hutton Institute PhD Opportunities
Supervisors. Lead supervisor - Dr Martin Balcerowicz, University of Dundee. Second supervisor - Dr Craig Simpson, James Hutton Institute. Read more
 Supervisors: Dr M Balcerowicz, Dr C Simpson, Ms G MacDonald
 31 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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BARIToNE: Improving barley climate resilience using a candidate gene approach (Project code 24H)

University of Dundee School of Life Sciences
Supervisors. Lead supervisor - Dr Martin Balcerowicz, University of Dundee. Second supervisor - Dr Craig Simpson, James Hutton Institute. Read more
 Supervisors: Dr M Balcerowicz, Dr C Simpson, Ms G MacDonald
 31 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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The analysis of HIF function in DNA repair and genome stability

University of Sheffield School of Biosciences
DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more
 Supervisors: Dr F Van Eeden, Prof S El-Khamisy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanisms controlling gene expression in hypoxia and inflammation

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Oxygen is one of the most important molecules for life. Every member of the animal kingdom depends on oxygen to help metabolize its food and drive many critical processes in metabolism. Read more
 Supervisor: Prof S Rocha
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Circadian mechanisms in psoriasis: therapeutic opportunities

The University of Manchester Faculty of Biology, Medicine and Health
Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more
 Supervisors: Dr H Young, Dr I Iqbal, Prof D Ray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Human Genetics, Genomics and Disease: Sequence determinants of mRNA fate in neuronal differentiation

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center Berlin Institute for Medical Systems Biology, Berlin, Germany. Read more
 Supervisor: Dr G Kudla
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more
 Supervisors: Dr G Galea, Prof J Sowden
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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