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Genetics (transgenic) PhD Projects, Programs & Scholarships

We have 14 Genetics (transgenic) PhD Projects, Programs & Scholarships

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  QUADRAT DTP: Actions of early life endocrine-disrupting chemical exposure on adult fish health using the zebrafish model
  Prof S Martin, Prof G Hardiman
Application Deadline: 22 January 2020

Funding Type

PhD Type

Landfills and other legacy waste sites in coastal zones are major sources of persistent organic pollutants (POPs), including polychlorinated biphenyl (PCBs), Perfluoroalkyl substances (PFASs) and polybrominated diphenyl ethers (PBDEs), to transitional waters and marine environments.
  Egr2 and 3 mediated T cell tolerance in cancer and their impact in immune checkpoint therapy
  Dr S Li
Applications accepted all year round

Funding Type

PhD Type

Tumour infiltrated lymphocytes (TILs) contain tumour reactive T cells and have been used as adoptive cell transfer therapy in patients which can mediate cancer regression.
  Cellular cross-talk at the perivascular niche and the blood brain barrier
  Prof B Hogan
Applications accepted all year round

Funding Type

PhD Type

Much research on vasculature has focussed on the endothelial cells that line functional vessels, however the milieu of cells that surround vessels (mural cells) play important and under-appreciated roles in homeostasis and disease.
  The Hippo pathway and Yap1 in vascular growth control in development and disease
  Prof B Hogan, Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Lymphatic vessels play roles in the drainage of tissue fluid, trafficking of immune cells and the metastatic spread of cancer.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round

Funding Type

PhD Type

The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Interneuron Development in the Zebrafish Spinal Cord
  Dr K Lewis
Applications accepted all year round

Funding Type

PhD Type

The Lewis Lab moved to Syracuse University from Cambridge University in the UK in 2010.
  (BBSRC DTP) Understanding the role of RNA binding proteins in the regulation of NF-kappa B dynamics, inflammation and cell death
  Prof M White, Dr A P Gilmore, Prof S Griffiths-Jones, Dr M Muldoon
Application Deadline: 31 January 2020

Funding Type

PhD Type

NF-kB is a key signalling system that controls inflammation and cell fate, dysregulation of which can lead to inflammatory disease or cancer.
  Generation of transplant tissue following correction of patient stem cells by genomic engineering
  Dr F Manson, Dr RL Taylor, Dr A Adamson
Applications accepted all year round

Funding Type

PhD Type

A number of retinal degenerations result from mutations in genes expressed in the retinal pigment epithelium (RPE) which lies under the photoreceptors.
  Identifying the evolutionary origins of the MADS-box floral quartet mechanism in seedless vascular plants
  Dr A.R.G Plackett, Dr J C Coates
Application Deadline: 31 March 2020

Funding Type

PhD Type

Despite its commonplace occurrence in today’s environment, the reproduction of plants via flowers and seeds is a recent evolutionary innovation arising from an ancestral seedless reproductive system similar to that still found in a subset of today’s plants (e.g.
  Understanding signalling networks underpinning key developmental processes during plant evolution
  Research Group: BBSRC MIBTP
  Dr J C Coates
Applications accepted all year round

Funding Type

PhD Type

Plants first appeared on land almost half a billion years ago. All land plants likely evolved from a single aquatic green algal ancestor.
  Analysis of the role of Hypoxia Inducibe Factor pathway in radioprotection
  Dr F Van Eeden
Application Deadline: 29 January 2020

Funding Type

PhD Type

Hypoxia inducible factor (HIF) is highly important in human health and disease, as is testified by the 2019 Nobel prize for Medicine or Physiology.
  Optogenetic programming of inflammation - in vivo Opto-GPCR approaches in neutrophils.
  Prof S Renshaw, Prof A Condliffe
Application Deadline: 29 January 2020

Funding Type

PhD Type

White blood cells called neutrophils have a powerful protective role and without them we develop overwhelming infection, yet they are also directly responsible for the tissue damage that characterises many common inflammatory diseases.
  Mapping neuromodulator networks in real-time in the model organism Caenorhabditis elegans
  Dr Y L Chew
Application Deadline: 30 April 2020

Funding Type

PhD Type

DEADLINE EXTENDED!. Background and Aims. Much of the efforts to identify neuronal connections and map the ‘connectome’ of the nervous system focuses on synaptic connections between neurons.
  Transcriptional battles in plant-pathogen interactions: understanding and re-wiring gene regulatory networks to enhance disease resistance
  Prof K Denby, Prof I A Graham
Application Deadline: 30 June 2020

Funding Type

PhD Type

The severity of plant disease is determined by a battle between pathogen virulence and host plant immunity – understanding this relationship is key to developing sustainable methods of pathogen control.
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