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Genetics (flow cytometry) PhD Projects, Programs & Scholarships

We have 18 Genetics (flow cytometry) PhD Projects, Programs & Scholarships

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  Analysing immune responses to metastatic ovarian tumours to identify therapeutic targets
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Investigating how ovarian tumours avoid immune responses in cancer patients
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
  Dr S Eyre, Mr P Martin, Dr AM Morris
Applications accepted all year round

Funding Type

PhD Type

Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect.
  Post-transcriptional regulation of transferrin receptor expression in Trypanosoma brucei
  Dr C Tiengwe
Applications accepted all year round

Funding Type

PhD Type

The goal of this project is to understand how. Trypanosoma brucei. controls expression of iron regulatory proteins in response to changes in intracellular iron.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round

Funding Type

PhD Type

Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
  Role of telomere attrition in cardiometabolic disease risk
  Dr J Buxton, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Common conditions such as Type 2 diabetes (T2D) and coronary artery disease (CAD) are complex disorders caused by a myriad of interacting genetic and lifestyle factors.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Therapy-induced senescence and stemness in ovarian cancer
  Prof R. Pearson, Dr K Chan
Applications accepted all year round

Funding Type

PhD Type

Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
  Development of iPSCs from patients with Urofacial Syndrome for disease modelling
  Prof S J Kimber, Prof A Woolf
Applications accepted all year round

Funding Type

PhD Type

Peripheral neuropathies (PNs) affect 2% of the general population. Somatic PNs cause locomotor and sensory deficits, while autonomic PNs cause cardiac dysrhythmias and gastrointestinal and urinary bladder dysfunction.
  Molecular modelling and analysis of plasma cell cancers
  Dr R Tooze, Dr G Doody, Dr R Owen
Application Deadline: 10 March 2020

Funding Type

PhD Type

Plasma cell neoplasms, including multiple myeloma, are cancers of the immune system that remain largely incurable despite major advances in therapy.
  Personalised anti-viral immunotherapies for hepatitis B and C virus-associated hepatocellular carcinoma
  Dr A Samson, Dr S Griffin
Application Deadline: 28 February 2020

Funding Type

PhD Type

Hepatocellular carcinoma (HCC) is a cancer of hepatocytes commonly caused by hepatitis B and C virus (HBV/HCV) infections. Only 12% of HCC patients survive for five-years, due to late diagnosis and inadequate non-personalised therapies.
  Expression systems for pluripotent stem cells and their differentiated derivatives
  Prof E Stanley, Prof AG Elefanty
Applications accepted all year round

Funding Type

PhD Type

Human pluripotent stem cells provide an opportunity to study normal development, to model disease and to generate cells and products for therapeutic use.
  In vitro models of type 1 diabetes.
  Prof E Stanley, Prof AG Elefanty
Applications accepted all year round

Funding Type

PhD Type

Type 1 diabetes is a condition in which the immune system destroys the cells that produce insulin, the hormone controlling the level of glucose in the blood stream.
  The role of the AXL Receptor Tyrosine Kinase in the DNA damage response
  Prof A Giaccia, Prof E Hammond
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The Axl receptor tyrosine kinase is a critical driver of tumour progression and drug resistance, and has resulted in combining Axl inhibitors with both targeted and cytotoxic therapies.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Hijacking of host cellular functions and metabolism in MRSA pathogenesis
  Dr M Letek, Dr V Behrends, Dr Y Calle
Applications accepted all year round

Funding Type

PhD Type

Applications are invited from potential PhD candidates to work at the Department of Life Sciences, University of Roehampton, supervised by Dr Michal Letek, Dr Volker Behrends, and Dr Yolanda Calle-Patino.
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