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Genetics (january) PhD Projects, Programs & Scholarships

We have 42 Genetics (january) PhD Projects, Programs & Scholarships

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  Biodiversity conservation ex situ or in situ with a focus on genetic diversity.
  Dr N Maxted
Applications accepted all year round

Funding Type

PhD Type

Field studies, ecogeography, geographic information systems and estimation of patterns of genetic diversity, IUCN taxonomic and genetic threat assessment will help elucidate conservation strategies and taxonomic clarity of critically endanged plant species.
  Determining novel molecular regulators of necrosis controlling premature cell death
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases.
  Regulation of apoptosis-induced compensatory cell proliferation and its implications for cancer and tissue regeneration
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage.
  18 doctoral research positions in the International Research Training Group (IRTG) 2290 “ALLIANCE BERLIN-CANBERRA: CROSSING BOUNDARIES IN MALARIA RESEARCH”

Funding Type

PhD Type

Funded by the Deutsche Forschungsgemeinschaft (DFG, German research foundation) and the Australian National University (ANU) invites applications for 18 doctoral research positions (11 positions at the Humboldt University (HU) in Berlin starting 1st Sept 2020 and 7 positions the Australian National University (ANU) in Canberra starting 1st January 2021).
  Conservation Genomics and Epigenomics of Fragmented and Declining Populations
  Prof L Beheregaray
Applications accepted all year round

Funding Type

PhD Type

We are looking for a bright candidate for one PhD position associated with the project. “The evolutionary potential of fragmented and declining populations”.
  Fully-funded PhD positions in several natural sciences & engineering disciplines

Funding Type

PhD Type

Join an internationally renowned scientific community with the Hector FellowPhD program. PhD students benefit not only from the experience of the program, but also from the network of Hector Fellows.
  18 doctoral research positions in the International Research Training Group (IRTG) 2290 “ALLIANCE BERLIN-CANBERRA: CROSSING BOUNDARIES IN MALARIA RESEARCH”

Funding Type

PhD Type

Funded by the Deutsche Forschungsgemeinschaft (DFG, German research foundation) and the Australian National University (ANU) invites applications for 18 doctoral research positions (11 positions at the Humboldt University (HU) in Berlin starting 1st Sept 2020 and 7 positions the Australian National University (ANU) in Canberra starting 1st January 2021).
  Computational methods to explore the relationship between gut microbes, metabolites and human health
  Research Group: Twin Research & Genetic Epidemiology
  Dr C Menni, Assoc Prof A Valdes
Applications accepted all year round

Funding Type

PhD Type

Start date. 1st January 2020. Metabolomics and the gut microbiome are intricately involved in susceptibility and potentially monitoring of metabolic diseases.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round

Funding Type

PhD Type

Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  Open PhD positions - IMPRS for Heart and Lung Research

Funding Type

PhD Type

The International Max Planck Research School for Heart and Lung Research (IMPRS-HLR) offers up to ten positions to talented and enthusiastic students holding a relevant Master‘s degree.
  Using statistical and functional analysis to investigate the contrasting disease specific roles of IL6R and the chr17q12 locus in the development of rheumatoid arthritis and asthma
  Dr J Curtin, Prof A Simpson
Applications accepted all year round

Funding Type

PhD Type

The Arthritis Research UK and Respiratory Centres at the University of Manchester have extensive research programmes investigating the genetic components of rheumatoid arthritis (RA) and asthma.
  Characterisation of DNA-protein crosslink proteolysis repair in cancer and therapy
  Prof K Ramadan, Prof B Kessler
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. DNA-protein crosslinks (DPCs) are under-investigated DNA lesions caused by the covalent attachment of proteins to DNA.
  Combining CRISPR and RNAseq to dissect molecular circuits in a hypoxic tumour microenvironment
  Prof F Buffa, Prof A Harris, Dr V D'Angiolella
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The role of the microenvironment in driving tumour progression is increasingly recognized. Hypoxia is one of the key microenvironmental changes between tumour and normal tissue, and adaptation of cancer cells to this hostile environment contributes to their malignancy and aggressive phenotype.
  Cross presentation of antigens of recombinant overlapping peptides to optimise vaccines against tumour and infectious diseases
  Dr S Jiang, Dr N Burgess-Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. We have developed a technology to producing overlapping peptides - bacterial expression of an amino acid sequence corresponding to overlapping peptide sequences spanning the length of a protein of interest interspersed with enzymatic cleavage sites.
  DNA repair fidelity, radiosensitivity and cancer.
  Prof T Humphrey, Dr V D'Angiolella
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. With almost half of all cancer patients receiving radiotherapy, tumour-specific radiosensitization remains an important goal for cancer research.
  Hypoxia links the unfolded proteim response with the DNA damage response
  Prof E Hammond, Prof A Giaccia
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Regions of hypoxia (insufficient oxygen) occur in most if not all solid tumours and are clinically relevant as they correlate with poor patient prognosis and therapy resistance.
  Investigating how cells repair DNA damage during mitosis
  Dr A Blackford, Dr D Clynes
Application Deadline: 3 March 2020

Funding Type

PhD Type

DNA damage poses a serious threat to proper chromosome segregation during cell division, and if repaired incorrectly can cause cell death or cancer.
  Strategies to enhance efficacy of nucleotide therapeutics for targeted cancer therapy
  Prof K Vallis, Prof T Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Oligonucleotide (ON) drugs hold promise in cancer medicine as they offer exquisitely precise inhibition of DNA and RNA targets.
  Targeting DNA repair to overcome cancer therapy resistance
  Prof P McHugh, Prof T Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. DNA cross-linking drugs and radiotherapy (RT) are used to treat a range of tumours including many hard-to-treat cancers (e.g.
  Targeting telomere maintenance and repair in cancer.
  Dr D Clynes, Dr A Blackford
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Cancer occurs through the uncontrolled division of cells. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes called telomeres.
  The role of the AXL Receptor Tyrosine Kinase in the DNA damage response
  Prof A Giaccia, Prof E Hammond
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The Axl receptor tyrosine kinase is a critical driver of tumour progression and drug resistance, and has resulted in combining Axl inhibitors with both targeted and cytotoxic therapies.
  Ubiquitin signalling in the pathogenesis and therapy of glioblastoma
  Dr V D'Angiolella, Prof A Ryan
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Glioblastoma, the most common primary brain tumor in adults accounts for more than 4000 deaths every year in the UK.
  Building the skull – normal and abnormal development
  Prof A Wilkie, Dr S Twigg
Application Deadline: 24 July 2020

Funding Type

PhD Type

Using a combination of patient samples and mouse models, we study the causes and developmental origins of skull malformation. The work ranges from scanning human genome sequences for new mutations, to use of genome editing and single cell transcriptomics to model the developmental causes of these malformations in mice.
  Chromatin remodelling in health and disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 24 July 2020

Funding Type

PhD Type

It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Computational Functional Genomics
  Assoc Prof G Lunter
Application Deadline: 24 July 2020

Funding Type

PhD Type

We are interested in building computational models to understand and predict the functional consequences of mutations in the (human) genome.
  De Novo Mutations and Human Disease
  Prof A Goriely, Prof A Wilkie
Application Deadline: 24 July 2020

Funding Type

PhD Type

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
  Gene Regulatory Networks in Development and Disease
  Dr T Sauka-Spengler
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory focuses on deciphering gene regulatory networks that govern complex programmes during early vertebrate development.
  Genetic Architecture of Inherited Cardiomyopathy
  Prof M Farrall, Dr AG Goel, Prof H Watkins
Application Deadline: 24 July 2020

Funding Type

PhD Type

Studying genetic variation in cardiomyopathy and coronary artery disease across the entire allele frequency spectrum in order to identify causative genes and susceptibility loci.
  Genetics of inherited cardiovascular disease: Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Prof H Watkins, Prof H Ashrafian, Prof C Redwood, Prof M Farrall
Application Deadline: 24 July 2020

Funding Type

PhD Type

I have had a longstanding focus on inherited heart muscle diseases, in particular hypertrophic cardiomyopathy, which is a relatively common Mendelian condition which puts affected individuals at risk of sudden cardiac death.
  Integrative Computational Biology and Machine Learning
  Dr A Sahakyan
Application Deadline: 24 July 2020

Funding Type

PhD Type

In Sahakyan Group, we strive to make computational biology maximally independent from empirical experimental data, by basing our models and predictions on genomic sequences and core biological mechanisms.
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