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Genetics (knowledge) PhD Projects, Programs & Scholarships

We have 69 Genetics (knowledge) PhD Projects, Programs & Scholarships

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  A genetic investigation of human and non-human remains from Hadrian’s Wall and the northern frontier of the Roman empire (ref: SF18/APP/GRAHAM)
  Dr E Graham
Applications accepted all year round

Funding Type

PhD Type

Over the past decade, advances in genetic technologies have made it possible to determine much more information from a sample of DNA.
  New Privilege nutrients of Human Gut Microbiota from Western Diet (ref: SF18/APP/Munoz)
  Dr J Munoz
Applications accepted all year round

Funding Type

PhD Type

The human large bowel contains ~1013 bacteria, referred to as the human gut microbiota or HGM. There is considerable interest in deploying prebiotic and probiotic strategies to maximise the impact of the HGM on human health.
  Defining the role of p53 in cancer immunotherapy
  Prof Y. Haupt, Dr S. Haupt, Dr P. Neeson
Applications accepted all year round

Funding Type

PhD Type

Despite clear evidence of an association between the tumour suppressor p53 and immunity, a gap in knowledge exists regarding its role in modulating immune responses, or its value in predicting patient responses to immunotherapy.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  To determine if N and P availability in the environment explains why most plant genomes are small, despite a huge range in angiosperm genome sizes.
  Prof AR Leitch, Dr IJ Leitch
Application Deadline: 27 June 2019

Funding Type

PhD Type

Angiosperms (flowering plants) not only have the largest range in genome size (GS) for any comparable eukaryotic group, varying c.
  Eukaryotic gene expression: understanding the role of UPF1 in global mRNA processing and amyotrophic lateral sclerosis (ALS)
  Dr S Brogna
Applications accepted all year round

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Funding Type

PhD Type

Good degree in the Physical or Life Sciences? Interested in biological or medical research? We offer fully-funded PhD places across the Oxford Doctoral Training Centre programmes.
  Statistical Genetics: Novel statistical method development for discovery and interpretation of genetic contribution to human haematological traits
  Dr V Iotchkova
Application Deadline: 19 July 2019

Funding Type

PhD Type

Genetic and epidemiological research has generated a vast amount of data and expertise for evaluating the genetic contribution to human traits in health and disease.
  Hijacking of host cellular functions and metabolism in MRSA pathogenesis
  Dr M Letek, Dr V Behrends, Dr Y Calle
Applications accepted all year round

Funding Type

PhD Type

Applications are invited from potential PhD candidates to work at the Department of Life Sciences, University of Roehampton, supervised by Dr Michal Letek, Dr Volker Behrends, and Dr Yolanda Calle-Patino.
  A fully funded PhD project: Climate change, plasticity & Aging in Sydney, Australia
  Prof S Nakagawa, Prof T Rogers, Dr S Drobniak
Application Deadline: 12 July 2019

Funding Type

PhD Type

UNSW, Sydney has announced another round of prestigious PhD scholarship (http://www.2025.unsw.edu.au/apply). We have been lucky enough to have been awarded one of these positions.
  PhD Project related to Spatial Proteomics of Protein quality control or Single Cell Gene Expression Dynamics
  Prof M Knop
Application Deadline: 30 July 2019

Funding Type

PhD Type

Project topic. Protein homeostasis involves control over spatio-temporal distribution of each individual protein species inside a cell.
  Understanding the role of TNFRSF11B polymorphisms in osteoprotegerin bioavailability and bone metabolism
  Dr A Daroszewska, Prof R van ‘t Hof
Applications accepted all year round

Funding Type

PhD Type

This project will focus on determining the effect of the polymorphisms of the TNFRSF11B gene, which encodes osteoprotegerin (OPG), on bone metabolism.
  Patient experience of the Mesothelioma Stratified Therapy Trial (MiST): a qualitative study
  Prof A Tod, Dr B Taylor
Application Deadline: 3 July 2019

Funding Type

PhD Type

This PhD provides a unique opportunity for a student to conduct a qualitative patient experience health services research study within a complex stratified clinical trial for people with malignant mesothelioma (MM), the Mesothelioma Stratified Therapy Trial (MiST).
  Learning from the past to predict and reduce the risk of infectious disease pandemics
  Dr F Perez-Reche, Prof N Strachan
Applications accepted all year round

Funding Type

PhD Type

The World Health Organisation reports that infectious diseases cause 63% of childhood deaths and 48% of premature deaths. There is the ongoing risk of epidemics and pandemics that can cause widespread morbidity and mortality (Spanish flu, ebola, SARS, E.
  Characterisation of SNA-2, a potential target for new drugs against parasitic nematodes.
  Dr B Mueller, Dr J Pettitt
Application Deadline: 28 June 2019

Funding Type

PhD Type

Spliced leader trans-splicing is a conserved and essential step involved in gene expression in many animal and human parasites that is responsible for the formation of mRNA 5’ ends in these organisms.
  Use of hair sample in Drug Facilitated Sexual Assault (DFSA) cases
  Research Group: Forensic & Investigative Sciences Research Group
  Dr L Gautam, Dr J Morrissey
Applications accepted all year round

Funding Type

PhD Type

Research Group. Forensic & Investigative Sciences Research Group - https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/forensic-and-investigative.
  Winter activity in the buff-tailed bumblebee (Bombus terrestris): how is diapause controlled in a commercially important pollinator?
  Research Group: Applied Ecology Research Group (AERG)
  Dr T Ings, Dr P Celis
Applications accepted all year round

Funding Type

PhD Type

Research Group. Applied Ecology Research Group (AERG). https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/applied-ecology.
  How do cancer cells manipulate protein production rates using different levels of gene expression to deliver proliferative or secretory phenotypes?
  Dr C Miller
Application Deadline: 24 June 2019

Funding Type

PhD Type

The Cancer Research UK Beatson Institute in Glasgow is one of the world-leading centres for cancer research. The Institute provides an outstanding research environment, underpinned by state-of-the-art core services and advanced technologies with special emphasis on imaging, metabolomics and in vivo models of cancer.
  Investigating Noise in Ageing Cellular Power Stations
  Dr N Jones
Applications accepted all year round

Funding Type

PhD Type

PhD Project. Imperial College Mathematics. Student Background. Theoretical Physics, Mathematics/Statistics, Electrical Engineering (Biological knowledge not required).
  IMPRS “From Molecules to Organisms”

Funding Type

PhD Type

Our PhD program in the life sciences places special emphasis on interdisciplinary interactions. We want to train the next generation of scientists to study complex biological processes that cannot be adequately understood within the limits of a single discipline.
  Activation of targeted DNA Damage Response as a novel therapy for Ovarian Cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer and accounts for 70% of all ovarian cancer deaths.
  Analytic methods for detecting and making sense of somatic genomic rearrangements
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Characterize the role of Treacle (TCOF1) in AKT-regulated ribosome biogenesis
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Ribosomes are essential for cell growth and proliferation, and their biogenesis requires exquisite regulation.
  Clinical cancer bioinformatics: developing new bioinformatics methods for improved analysis of cancer gene hybridisation capture panels
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Control of tissue growth and cancer by the Hippo pathway
  Dr K. Harvey, Dr C Poon
Applications accepted all year round

Funding Type

PhD Type

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have drawn conclusions about gene function using indirect techniques that only allow us to infer what a gene normally does, without actually watching it work.
  Development of targeted therapy for acute myeloid leukaemia with mutations in isocitrate dehysdrogenase
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

Acute Myeloid Leukaemia (AML) is an aggressive disease with poor prognosis and development of novel treatment options is urgently needed.
  Exploration of novel approaches to anti-cancer treatment: manipulation of mutant p53
  Prof Y. Haupt, Dr S. Haupt
Applications accepted all year round

Funding Type

PhD Type

P53 is the most mutated gene in human cancer, affecting about half the cases of human cancer. We have recently identified novel regulators of mutant p53 using sophisticated loss of function whole genome high through put screen (image 1).
  Finding a therapy for triple negative breast cancer patients
  Dr K. Britt
Applications accepted all year round

Funding Type

PhD Type

Triple negative breast cancers are a poor prognosis breast cancer with limited therapeutic options as they do not express estrogen receptors, progesterone receptors or Her2.
  How is fate determined during T cell development, leukemogenesis and responses?
  Dr S. Russell
Applications accepted all year round

Funding Type

PhD Type

Understanding how cell fate programming works will lead to improved diagnostic and therapeutic opportunities for leukemia, and to improved immunotherapies for cancer and infectious disease.
  Immunostaging for melanoma to accurately predict the risk of relapse after surgery
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

This project will utilise a large biobank of clinically annotated samples from patients with melanoma at high risk of relapse after surgery to develop a signature that predicts risk of relapse.
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