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Genetics (transgenic) PhD Projects, Programs & Scholarships

We have 20 Genetics (transgenic) PhD Projects, Programs & Scholarships

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  Analysis of the role of Hypoxia Inducibe Factor pathway in radioprotection
  Dr F Van Eeden
Applications accepted all year round

Funding Type

PhD Type

Hypoxia inducible factor (HIF) is highly important in human health and disease, as is testified by the 2019 Nobel prize for Medicine or Physiology.
  Egr2 and 3 mediated T cell tolerance in cancer and their impact in immune checkpoint therapy
  Dr S Li
Applications accepted all year round

Funding Type

PhD Type

Tumour infiltrated lymphocytes (TILs) contain tumour reactive T cells and have been used as adoptive cell transfer therapy in patients which can mediate cancer regression.
  Cellular cross-talk at the perivascular niche and the blood brain barrier
  Prof B Hogan
Applications accepted all year round

Funding Type

PhD Type

Much research on vasculature has focussed on the endothelial cells that line functional vessels, however the milieu of cells that surround vessels (mural cells) play important and under-appreciated roles in homeostasis and disease.
  The Hippo pathway and Yap1 in vascular growth control in development and disease
  Prof B Hogan, Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Lymphatic vessels play roles in the drainage of tissue fluid, trafficking of immune cells and the metastatic spread of cancer.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round

Funding Type

PhD Type

The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Interneuron Development in the Zebrafish Spinal Cord
  Dr K Lewis
Applications accepted all year round

Funding Type

PhD Type

The Lewis Lab moved to Syracuse University from Cambridge University in the UK in 2010.
  Local gene drives for mosquitoes
  Dr M Anderson, Dr R Noad, Prof L Alphey
Application Deadline: 28 February 2020

Funding Type

PhD Type

A PhD studentship funded by The Pirbright Institute is available to highly motivated students interested in genetic control of mosquitoes.
  Generation of transplant tissue following correction of patient stem cells by genomic engineering
  Dr F Manson, Dr RL Taylor, Dr A Adamson
Applications accepted all year round

Funding Type

PhD Type

A number of retinal degenerations result from mutations in genes expressed in the retinal pigment epithelium (RPE) which lies under the photoreceptors.
  Sexual Selection and Sexual Conflict in Hermaphrodites
  Dr L Scharer
Application Deadline: 28 February 2020

Funding Type

PhD Type

A PhD position, funded by the Swiss National Science Foundation (SNSF), is available in the Schärer Group (http://evolution.unibas.ch/scharer/) at the Zoological Institute, University of Basel, Switzerland.
  Identifying the evolutionary origins of the MADS-box floral quartet mechanism in seedless vascular plants
  Dr A.R.G Plackett, Dr J C Coates
Application Deadline: 31 March 2020

Funding Type

PhD Type

Despite its commonplace occurrence in today’s environment, the reproduction of plants via flowers and seeds is a recent evolutionary innovation arising from an ancestral seedless reproductive system similar to that still found in a subset of today’s plants (e.g.
  Understanding signalling networks underpinning key developmental processes during plant evolution
  Research Group: BBSRC MIBTP
  Dr J C Coates
Applications accepted all year round

Funding Type

PhD Type

Plants first appeared on land almost half a billion years ago. All land plants likely evolved from a single aquatic green algal ancestor.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Prof J Fallowfield
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  Fully funded PhD Studentship opportunities in the Neuroscience Institute at the University of Sheffield

Funding Type

PhD Type

The Neuroscience Institute at the University of Sheffield is currently recruiting for. ● Two 3.5 year home/EU PhD Studentships funded by The University of Sheffield.
  Investigation of DNA/RNA Instability in Neurological Disease
  Prof S El-Khamisy, Dr G Hautbergue, Dr F Van Eeden
Application Deadline: 31 March 2020

Funding Type

PhD Type

Our genome is constantly threatened by environmental and endogenous stressors. One consequence of this threat is the formation of the rather unusual nucleic acid structures involving a duplex DNA and RNA, called DNA/RNA hybrids (R-loops).
  Mapping neuromodulator networks in real-time in the model organism Caenorhabditis elegans
  Dr Y L Chew
Application Deadline: 15 March 2020

Funding Type

PhD Type

APPLICATIONS CLOSING - Shortlisted applications will be contacted for interview by mid March. IMPORTANT NOTE. Due to the high volume of applications, there will unfortunately not be feedback or responses to all applicants.
  Transcriptional battles in plant-pathogen interactions: understanding and re-wiring gene regulatory networks to enhance disease resistance
  Prof K Denby, Prof I A Graham
Application Deadline: 30 June 2020

Funding Type

PhD Type

The severity of plant disease is determined by a battle between pathogen virulence and host plant immunity – understanding this relationship is key to developing sustainable methods of pathogen control.
  Identification of the molecular pathways that guide zebrafish regeneration.
  Dr H Roehl
Applications accepted all year round

Funding Type

PhD Type

The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged.
  Regulation of cell cycle progression in skeletal muscle stem cells
  Dr A G Borycki
Applications accepted all year round

Funding Type

PhD Type

The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells called satellite cells.
  Role of primary cilia in skeletal muscle stem cells and muscle regeneration.
  Dr A G Borycki
Applications accepted all year round

Funding Type

PhD Type

Primary cilia are ancient organelles present at the surface of many cell types in vertebrates. In recent years, they have been shown to play essential roles in relaying sensory and signalling information from the environment to the cell.
  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
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