This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 21 studentships for entry in September 2025. Read more
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 21 studentships for entry in September 2025. Read more
Are you eager to join an international community of scientists to tackle novel and exciting research projects in the areas of biochemistry, structural biology, biophysics, cell biology, chemical biology and synthetic biology?. Read more
The neural circuit wiring diagram varies across sexes. In the adult fly, the gene fruitless has been associated with prominent changes across the nervous system between males and females. Read more
A direct consequence of the universality of the genetic code is the possibility for genetic information to be transferred between evolutionarily distant species. Read more
The overall goal of our research is to discover the circuit implementation of learning and action selection. Since these functions likely emerge from… Read more
The Robertson lab develops genome engineering tools for the de novo synthesis of non-model gut bacteria, with the ultimate aim of reprogramming the microbiome to study and modulate human health. Read more
TB remains the world’s greatest infectious killer despite a vaccine (BCG) for a century and effective antibiotics for 60 years. TB’s persistence over millennia in the face of major medical advances underscores the ability of Mycobacterium tuberculosis to evade and exploit host defences and antibiotics. Read more
Large multiprotein complexes perform many essential functions in eukaryotic cells. My lab purifies, assays and determines structures of these macromolecular machines to understand their mechanisms. Read more
TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more
A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of self-replication as well as mutation, and hence evolution towards ever more efficient replication. Read more
The complexity of eukaryotic life forms is driven by RNA polymerase II (Pol II), which transcribes all protein-coding genes and thousands of non-coding RNA loci. Read more
Project Overview. The Wilkinson research group focuses on the biology and translational applications of blood-forming haematopoietic stem cells (HSCs). Read more
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