Genetics (cell therapy) PhD Projects, Programmes & Scholarships for UK Students

We have 6 Genetics (cell therapy) PhD Projects, Programmes & Scholarships for UK Students

Advancing translational cell therapy for Hirschsprung disease

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Clinical disorders characterised by neuronal loss or dysfunction in the gastrointestinal tract remain some of the most challenging to manage, with considerable morbidity and mortality and very limited treatments. Read more

Supervisors: Dr C McCann, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more

Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: MRC Human Genetics Unit

Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more

Supervisor: Dr NB Benabdallah

19 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Utilising genetic and genomic predictors of vasculitis and disease/treatment complications for application in routine clinical practice

University of Leeds Faculty of Medicine and Health

There is substantial interest in using genetic biomarkers to predict those most at risk of disease and treatment complications; this is one of the focuses of Our Future Health, a national study aiming to recruit 5M participants ( https://ourfuturehealth.org.uk/ ). Read more

Supervisors: Prof A Morgan, Dr MM Iles, Dr R Mujica-Mota

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more

Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 6 Genetics (cell therapy) PhD Projects, Programmes & Scholarships for UK Students

Genetics (cell therapy) PhD Projects, Programmes & Scholarships for UK Students

We have 6 Genetics (cell therapy) PhD Projects, Programmes & Scholarships for UK Students

Advancing translational cell therapy for Hirschsprung disease

Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

NIHR Leeds BRC: Utilising genetic and genomic predictors of vasculitis and disease/treatment complications for application in routine clinical practice

A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

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