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We have 11 Genetics (mr) PhD Projects, Programmes & Scholarships for UK Students

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Genetics (mr) PhD Projects, Programmes & Scholarships for UK Students

We have 11 Genetics (mr) PhD Projects, Programmes & Scholarships for UK Students

Mendelian Randomisation for mediation analysis with multiple mediators: theory and applications

Rationale. Many of an individual’s traits are observationally associated with their health outcomes. Understanding the relationships between these factors is critical to effective public health intervention. Read more

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

Rationale. Mendelian Randomization (MR) is a genetic epidemiology method which utilises variants sourced from genome-wide association studies (GWAS) to assess causality between risk/protective factors and disease outcomes in a manner less biased to observational studies(1). Read more

How does parental education increase risk to ADHD in the offspring?

Rationale. Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental condition, characterised by persistent difficulties in the areas of attention span/impulse control. Read more

Identifying causal pathways to disease using DNA methylation predicted blood traits.

Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more
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