University of Bristol Genetics PhD Projects, Programmes & Scholarships

We have 30 University of Bristol Genetics PhD Projects, Programmes & Scholarships

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Funded PhD - The mechanisms of cognition in bees and flies

University of Bristol School of Physiology, Pharmacology & Neuroscience

This project will be part of the Bristol-Macquarie Cotutelle Programme, funded by EPSRC. Read more

Supervisor: Prof J Hodge

1 August 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Funded PhD - Determining the genetic and circadian basis of bipolar disorder

University of Bristol School of Physiology, Pharmacology & Neuroscience

This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more

Supervisors: Prof J Hodge, Dr AF French

12 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Younger, happier and more productive plants: using developmental genetics to improve herb yields and quality

University of Bristol School of Biological Sciences

If you’ve ever grown coriander at home you’ll have noticed that once the plant flowers it no longer produces the leaves used for seasoning. Read more

Supervisor: Dr J Fouracre

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

University of Bristol School of Physiology, Pharmacology & Neuroscience

Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more

Supervisor: Prof J Hodge

Year round applications PhD Research Project Self-Funded PhD Students Only

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MScR - In vivo characterisation of novel risk genes for Alzheimers disease identified by Genome Wide Association Studies

University of Bristol School of Physiology, Pharmacology & Neuroscience

Genome Wide Association Studies (GWAS) for Alzheimer’s disease (AD) have identified a number of genes that are significantly associated with the disease (van der Kant et al., 2019). Read more

Supervisor: Prof J Hodge

Year round applications PhD Research Project Self-Funded PhD Students Only

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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School

Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more

Supervisor: Dr J Min

Year round applications PhD Research Project Self-Funded PhD Students Only

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Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

University of Bristol Bristol Medical School

Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more

Supervisor: Prof S Satchell

Year round applications PhD Research Project Self-Funded PhD Students Only

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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School

Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more

Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Estimating the global cancer burden due to low levels of physical activity

University of Bristol Bristol Medical School

Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more

Supervisors: Dr S Lewis, Prof R Martin, Dr R Pulsford, Prof R Jago, Dr FB Bray

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

Rationale. Mendelian Randomization (MR) is a genetic epidemiology method which utilises variants sourced from genome-wide association studies (GWAS) to assess causality between risk/protective factors and disease outcomes in a manner less biased to observational studies(1). Read more

Supervisors: Prof T Gaunt, Dr M Sobczyk

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Prospectively mapping the development of liver disease amongst young adults. Who is developing it early and why?

University of Bristol Bristol Medical School

Rationale. Historically, cirrhosis (irreversible liver scarring), often due to alcohol-related liver disease (ARLD) and non-alcoholic fatty liver disease (NAFLD), presents in the 5th and 6th decade. Read more

Supervisors: Dr KA Abeysekera, Prof M Hickman, Prof N Timpson

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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The genetics of human scarring – cross-cutting approaches to the understanding of human wound repair.

University of Bristol Bristol Medical School

Rationale. Repair of adult tissues involves a complex interplay of several key cell lineages and inevitably leads to formation of a fibrotic collagenous scar. Read more

Supervisors: Prof N Timpson, Prof P Martin

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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How does parental education increase risk to ADHD in the offspring?

University of Bristol Bristol Medical School

Rationale. Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental condition, characterised by persistent difficulties in the areas of attention span/impulse control. Read more

Supervisors: Dr E Stergiakouli, Dr L Howe, Dr AH Havdhal

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

University of Bristol Bristol Medical School

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

Supervisors: Dr P Yousefi, Prof R Martin, Dr M Suderman, Dr A Lane, Dr SM Merriel

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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We have 30 University of Bristol Genetics PhD Projects, Programmes & Scholarships

University of Bristol Genetics PhD Projects, Programmes & Scholarships

We have 30 University of Bristol Genetics PhD Projects, Programmes & Scholarships

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