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University of Manchester Genetics PhD Projects, Programs & Scholarships

We have 49 University of Manchester Genetics PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 49
  (BBSRC DTP) Cardiac Physiology in the World’s Oldest Vertebrate, The Greenland Shark
  Dr H Shiels, Dr G Galli, Dr A Stevens, Dr C Pinali
Application Deadline: 31 January 2019
The life span of the Greenland shark is at least 272 years and may be as long as 500 years making this animal the longest living vertebrate on the planet1.
  (BBSRC DTP) Elucidating the responses to nascent protein misfolding and aggregation stress
  Prof C M Grant, Prof S Hubbard, Prof M Ashe
Application Deadline: 31 January 2019
The aim of this study is to characterize the proteins that aggregate during nascent protein misfolding and to investigate how cells mitigate the damaging effects of aggregate formation.
  (BBSRC DTP) Exploiting plant diversity to make a new biomaterials
  Prof S Turner, Prof V Allan, Prof S Flitsch
Application Deadline: 31 January 2019
It is clear that there is now enormous pressure to develop much better replacements for plastics synthesised from fossil fuels.
  (BBSRC DTP) Extracellular regulation of BMP signalling in development and disease
  Prof H Ashe, Prof C Baldock
Application Deadline: 31 January 2019
The Bone Morphogenetic Protein (BMP) pathway, one of the major cell signalling pathways, is important for development of nearly all human organs and tissues.
  (BBSRC DTP) Microbial population diversity as a driver of antibiotic resistance evolution
  Dr D Gifford, Dr C Knight, Dr T Gilman
Application Deadline: 31 January 2019
Classically, microbial evolution has been thought to progress via rapid sweeps of beneficial mutations that quickly fix within populations—the so-called ‘strong selection, weak mutation’ model.
  (BBSRC DTP) Morphological control of cell fate, behaviour and function
  Dr S Herbert, Prof N Papalopulu, Dr M Baron
Application Deadline: 31 January 2019
Tissue formation critically depends on the appropriate assignment of specialised cell fates and behaviours. The traditional perspective of these competitive decisions is that cells first perceive extrinsic signalling cues, decide their fate and then act appropriately (i.e.
  (BBSRC DTP) Probing Regulatory Networks setting Notch signalling levels in vivo in Drosophila and Zebrafish.
  Dr M Baron, Dr S Herbert, Prof S Hubbard
Application Deadline: 31 January 2019
Development of organisms and maintenance of healthy tissues depends on proper control of cell to cell communication networks that control cell fate and behaviour.
  (BBSRC DTP) The role of clock dysfunction in obesity-related inflammation and insulin resistance
  Dr D Bechtold, Dr S Cruickshank, Dr I Iqbal
Application Deadline: 31 January 2019
Obesity is one of the biggest challenges to public health in the UK and across much of the world. The major threat is in obesity-related metabolic disturbances, which drive insulin resistance, type-2 diabetes, and cardiovascular disease.
  Assembly of the DNA competence uptake pathway in Gram negative bacteria
  Prof J P Derrick, Dr F Hayes
Applications accepted all year round
Bacteria can take up DNA by three main mechanisms, transduction, conjugation and natural transformation, the latter being frequently termed ‘natural competence’.
  Bacteriophages of Gram positive bacteria: gateways to infection control
  Dr G Xia, Prof J P Derrick
Applications accepted all year round
The rise in antibiotic resistance has prompted a renewed interest in bacteriophage research. A study of the molecular basis for recognition of the bacterial host has applications in detection, vaccine design and control of bacterial infections.
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