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Immunology (genetic manipulation) PhD Projects, Programs & Scholarships

We have 5 Immunology (genetic manipulation) PhD Projects, Programs & Scholarships

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We have 5 Immunology (genetic manipulation) PhD Projects, Programs & Scholarships

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Tumour metabolic and immune landscape in spatial resolution: using engineered bacterial cancer therapy to enhance anti-tumour T cell responses

Bacterial cancer therapy (BCT) is a promising and versatile therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is the most well-studied among bacterial vectors due to advantages in ease of genetic modification, metabolic adaptation, and motility. Read more

Understanding complement system dysregulation in the tumour microenvironment

Inducing a stress response analogous to anti-viral immunity is important for maximising immune responses against the tumour. However, tumours evolve evasion strategies that can limit these responses. Read more

What is the role of intestinal mucins in health maintenance during ageing?

An increasing proportion of our population falls within the elderly age bracket. As a result, the identification of interventions that help people stay healthy into their old age is one of the most significant challenges facing biomedical research. Read more

Precision Medicine DTP – Defining the impact of androgens on uterine immune cell function during endometrial tissue repair

  Research Group: Centre for Inflammation Research
Background. Endometrial repair is essential for women’s reproductive health. One in three women in the UK will suffer from a reproductive health problem such as polycystic ovarian syndrome, heavy menstrual bleeding or endometriosis. Read more

Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more
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