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Immunology (metabolism) PhD Projects, Programs & Scholarships

We have 33 Immunology (metabolism) PhD Projects, Programs & Scholarships

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We have 33 Immunology (metabolism) PhD Projects, Programs & Scholarships

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KIRC1: Metabolism in inflamed immune microenvironment

CLINICAL OPTION. Immune responses differ drastically depending on where they occur. Tissue microenvironments help control immunity by providing signalling cues, cellular interactions, and importantly, determining the supply of nutrients and metabolites. Read more

NCKIR10: Metabolism in inflamed immune microenvironments

NON-CLINICAL OPTION. Immune responses differ drastically depending on where they occur. Tissue microenvironments help control immunity by providing signalling cues, cellular interactions, and importantly, determining the supply of nutrients and metabolites. Read more

How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more

Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

Iron Biology

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism. Read more

Iron Biology

We study how iron and anaemia influence immunity and infectious diseases. Our research inspires therapies that control iron physiology to improve immunity, combat infections and treat disorders of iron metabolism. Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Tumour metabolic and immune landscape in spatial resolution: using engineered bacterial cancer therapy to enhance anti-tumour T cell responses

Bacterial cancer therapy (BCT) is a promising and versatile therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is the most well-studied among bacterial vectors due to advantages in ease of genetic modification, metabolic adaptation, and motility. Read more

mRNA-selective translational control required for B-cell proliferation

Industrial Supervisor. Neil Jones (Cancer Research UK-Therapeutic Discovery Laboratories) . The Babraham Research Campus (BRC) is pleased to announce that it has been awarded a BBSRC Collaborative Training Partnership (CTP) Award for 15 PhD Studentships (5 per year for 3 years) to start in October 2022. Read more

Covalent Recruitment of Polymer Therapeutics

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details. Read more

(BBSRC DTP) Defining the roles of mRNA methylation in circadian physiology and inflammation

Methylation is a pervasive biochemical modification targeting virtually all types of molecules in our cells. A key metabolic pathway called the “methyl cycle” synthesises S-adenosylmethionine (SAM), the methyl donor co-substrate used by over 200 substrate-specific methyltransferases described so far in humans. Read more

Self-funded BMS project: Ion channel signalling in cancer cells

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more

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