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We have 49 Immunology (treatment) PhD Projects, Programmes & Scholarships

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Immunology (treatment) PhD Projects, Programmes & Scholarships

We have 49 Immunology (treatment) PhD Projects, Programmes & Scholarships

The role of selective and novel biomarkers and their correlation with clinical outcome measures, pre and post-surgical treatment of benign and malignant disorders of the prostate

The Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS) is a novel initiative by the Betsi Cadwaladr University Health Board (BCUHB), and is designed to encourage and support research within the Health Board and to promote academic activity, basic science and clinical research across North Wales (UK) and beyond. Read more

NIHR Leeds BRC: Utilising genetic and genomic predictors of vasculitis and disease/treatment complications for application in routine clinical practice

There is substantial interest in using genetic biomarkers to predict those most at risk of disease and treatment complications; this is one of the focuses of Our Future Health, a national study aiming to recruit 5M participants ( https://ourfuturehealth.org.uk/ ). Read more

Assessment of matrix metalloproteinase 9 inhibitor for the treatment of severe skin-blistering adverse drug reactions using in vitro and ex vivo skin models.

Stevens-Johnson syndrome and toxic epidermal necrolysis are rare, immune-related, severe skin-blistering reactions which can be caused by a wide range of commonly administered drugs. SJS/TEN is characterised by wide-spread skin (epidermal) detachment and recent work in our lab has identified a number of potential molecular mechanism by which this could occur. Read more

From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Developing 3D models to understand how interactions between bacterial biofilm and the host environment impact antimicrobial efficacy in a chronic infected wound

2.8 million people in the UK have a chronic wound which persist for months or years, causing pain, isolation, odour, and decreased mobility; patients with chronic wounds regularly report a deterioration in quality of life. Polymicrobial biofilms are present in greater than 70% of chronic wounds, making effective treatment incredibly challenging. Read more

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