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Immunology (behaviour) PhD Projects, Programs & Scholarships

We have 21 Immunology (behaviour) PhD Projects, Programs & Scholarships

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  How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
  Dr K Couper, Prof R K Grencis
Applications accepted all year round

Funding Type

PhD Type

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state.
  The impact of zinc deficiency on Alzheimer’s disease
  Dr C Lawrence, Prof D Brough
Applications accepted all year round

Funding Type

PhD Type

In addition to memory problems, people with Alzheimer’s disease (AD) also experience ‘non-memory’ behavioural symptoms including depression, anxiety, and agitation.
  Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy
  Prof K Gaston, Dr P-S Jayaraman
Applications accepted all year round

Funding Type

PhD Type

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies.
  Analysis of the exoribonuclease Rex1
  Dr P Mitchell
Applications accepted all year round

Funding Type

PhD Type

Inhibition of one exosome catalytic subunit renders cells dependent upon another RNase called Rex1.
  Investigating the molecular basis of this adhesion and the development of tetraspanin-based reagents for preventing bacterial infections
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Structural and functional characterisation of a novel cyanobacterial nanocompartment
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Increasing efficiency is an important driving force behind cellular organization and often achieved through compartmentalization.
  Tetraspanin structure and function
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Four Year PhDs in Cancer, Immunology and Biomedicine

Funding Type

PhD Type

The Faculty of Medicine at the University of Southampton has a strong reputation in research, enterprise and education, with an emphasis on translating new discoveries from basic science into clinical innovation.
  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  Understanding the role of DRAM in infection and autophagy-related disease
  Dr J King, Dr P Elks
Applications accepted all year round

Funding Type

PhD Type

Intracellular degradation by lysosomes is important in a wide range of diseases. The capture and degradation of cytoplasmic components by autophagy allows tumour cells to survive starvation and neurons to remove the protein aggregates associated with neurodegeneration.
  Project title: Elucidating the mechanisms of pathology in neurodevelopmental white matter diseases
  Dr N Hamilton
Applications accepted all year round

Funding Type

PhD Type

Our research interest is to dissect the mechanism of auto-inflammatory neurological disorders using zebrafish as an animal model.
  Four Year PhDs in Cancer, Immunology and Biomedicine

Funding Type

PhD Type

The Faculty of Medicine at the University of Southampton has a strong reputation in research, enterprise and education, with an emphasis on translating new discoveries from basic science into clinical innovation.
  Developing next generation bioimaging/biophotonics tools to dissect the immunological synapse in single cells, one molecule at a time
  Prof M Leake, Dr N Signoret
Application Deadline: 6 April 2020

Funding Type

PhD Type

We seek an ambitious PhD student to develop/apply new bioimaging/biophotonics tools to gain insight into complex biological processes across multiple length/timescales, from single molecules through to subcellular structures, cells and cellular populations.
  Ion channel signalling in cancer cells
  Dr W Brackenbury
Application Deadline: 30 June 2020

Funding Type

PhD Type

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing.
  Genome association studies to detect genetic determinants of virulence traits of invasive meningococcal disease isolates with age stratification
  Dr C D Bayliss
Applications accepted all year round

Funding Type

PhD Type

Neisseria meningitidis is the major cause of bacterial meningitis but is also widespread as an asymptomatic coloniser of human oropharyngeal tissues.
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