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We have 6 Immunology (macrophage) PhD Projects, Programmes & Scholarships

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Immunology (macrophage) PhD Projects, Programmes & Scholarships

We have 6 Immunology (macrophage) PhD Projects, Programmes & Scholarships

Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

SLS 3: Investigating the anti-inflammatory effects of artemisinin compounds on macrophages under systemic inflammatory conditions

Artemisinin compounds are safe and effective antimalarials. Recent evidence in our lab has shown these compounds also exert a potent anti-inflammatory effect by inhibiting neutrophil migration and the release of cytokines, chemokines and neutrophil extracellular traps. Read more

Investigating how tumour associated macrophages affect cancer metastasis and response to therapies

Solid tumours are generally highly infiltrated by macrophages. Macrophages are heterogeneous and different populations with different and sometimes even opposite functions co-exist in tumours affecting cancer progression. Read more
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