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Immunology (php) PhD Projects, Programs & Scholarships

We have 20 Immunology (php) PhD Projects, Programs & Scholarships

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  Resistance isn’t futile: Dissecting adaptation and antimicrobial resistance in pathogenic fungi
  Dr D Childers, Prof C Munro
Application Deadline: 31 January 2020

Funding Type

PhD Type

What will you investigate?. We have only four major classes of antifungals to treat life-threatening fungal infections, which even with treatment will claim over 1 million lives this year.
  Diet mediated metabolic-inflammation – mechanistic insights
  Prof H Roche, Dr Q Su
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Metabolic-inflammation is a critical process that underpins obesity related disease including diabetes and cancer biology.
  Investigation and exploration of health and therapeutic benefits of plant-derived secondary metabolites
  Dr C Situ, Prof J Bengoechea
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Plants and their products have revolutionarily shaped human development throughout history. The traditional plant-based medicine continues to play an essential role in the treatment of disease and in healthcare systems in many parts the world.
  Rewiring of host cell protein complexes by pathogen effectors - mass spectrometry-based methods and applications in infection biology
  Dr B Collins, Prof J Bengoechea, Dr G Schroeder
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Bacterial pathogens, such as Klebsiella pneumoniae and Legionella pneumophila, residing inside host immune cells such as macrophages, must subvert host cell defences in order to avoid destruction.
  Uncovering the Hidden Human Milk Microbiome
  Dr S Cameron, Prof S Huws, Dr J Megaw
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Until recently, human milk (HM) was considered to be sterile and free of microorganisms in healthy mothers. We are now beginning to understand the importance of the microbiome of HM and its role in developing the naïve immune system of new-born babies.
  Precision Medicine DTP - Analyzing network formation during brain tumour initiation
  Dr D Sieger, Prof P Uhlén
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. High grade brain tumours (HGBTs) represent a complex and devastating disease and are posing an unmet clinical need. These tumours resist multi-modal therapies and survival times are only 15 months on average.
  Precision Medicine DTP - Harnessing plasticity to repair spinal cord injury
  Dr T Becker, Prof C G Becker, Prof A El Manira
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. After a spinal cord injury in the zebrafish, lost neurons are replaced and axonal connections re-established (Tsarouchas et al., 2018).
  Precision Medicine DTP - How do IFITM proteins regulate the Interferon Related DNA-damage Resistance Signature (IRDS) and clinical outcomes in cancers of high unmet clinical need?
  Dr R Sloan, Prof K Ball, Dr S Wilson
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Interferon Induced Transmembrane proteins (IFITMs) are a family of innate immune membrane proteins that can inhibit viral infection at cell entry (e.g.
  Precision Medicine DTP - Identifying Pathogenic B cells in Rheumatoid Arthritis
  Research Group: Centre for Inflammation Research
  Dr M Gray, Prof C Goodyear, Dr G Cowan
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Rheumatoid Arthritis (RA) is the commonest, most destructive, autoimmune inflammatory arthritis, causing chronic pain, fatigue, depression and disability.
  Precision Medicine DTP – Integration of single-cell RNA sequencing data from human and murine kidney disease to identify novel therapeutic targets
  Research Group: Centre for Cardiovascular Science
  Dr BC Conway, Dr T Chandra, Dr D Ferenbach
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease and for end-stage kidney disease (ESRD), at which point patients require dialysis or transplantation.
  Precision Medicine DTP – Investigating disease causing mutations in PNPase- an approach to understand mitochondrial nucleic acid driven auto-inflammation
  Research Group: Centre of Genomic and Experimental Medicine
  Dr A Dhir, Dr S Tait, Dr T Chandra
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Mitochondrial diseases are a heterogeneous class of disorders often characterized by failure of mitochondrial function and loss of energy associated with respiratory chain complex deficiency.
  Precision Medicine DTP - Proteomic analysis of FAK function in human pancreatic cancer
  Research Group: Centre for Inflammation Research
  Dr A Serrels, Dr A Byron, Dr A von Kriegsheim
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. In the United Kingdom, the 5-year survival rate for patients with pancreatic ductal adenocarcinoma (PDAC) is just 3% (Cancer Research UK statistics), and as a result pancreatic cancer is the 4th most common cause of cancer death in the UK and US.
  Precision Medicine DTP - Stromal transcriptomic signatures in prostate cancer metastasis and hormone therapy resistance
  Research Group: MRC Centre for Reproductive Health
  Dr B Qian, Prof H Y Leung, Dr A Sims, Prof P Wiklund
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. A tremendous amount of cancer ‘-omics’ data have been generated with the intention to stratify patients for personalized diagnosis and treatment.
  Precision Medicine DTP - 3D Modeling of Changes in Genome Architecture in Development and Disease
  Research Group: Institute of Cell Biology
  Prof E Schirmer, Dr D Marenduzzo
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Defects in spatial genome organisation have recently been linked to human disease and the National Institutes of Health, USA director speculated that most as yet unidentified disease alleles will occur in non-coding genome regions.
  MRC Precision Medicine DTP: Proteome-level diversity in RNA viruses
  Research Group: Institute of Infection, Immunity & Inflammation
  Dr E Hutchinson, Dr R Burchmore
Application Deadline: 8 January 2020

Funding Type

PhD Type

Supervisors. Dr Edward Hutchison. Dr Richard Burchmore. Project summary. RNA viruses are major threats to human and animal health and account for the majority of emerging infectious diseases.
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