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Immunology (structural biology) PhD Projects, Programs & Scholarships

We have 18 Immunology (structural biology) PhD Projects, Programs & Scholarships

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  Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Application Deadline: 1 April 2020

Funding Type

PhD Type

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas.
  Simultaneous gene transcription and translation in bacteria
  Dr Gabriel Demo
Application Deadline: 20 February 2020

Funding Type

PhD Type

OBJECTIVES. The research aims to unravel the fundamental mechanism of the transcription-translation coupling in bacteria.
  The Biology of Parasitism in Parasitic Nematodes
  Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

We work on the biology of parasitic nematode worms, particularly Strongyloides spp. The recent, detailed characterisation of the Strongyloides genome (Hunt et al.
  Epigenetics and Cancer: Development of Novel Tools to Determine how Aberrant V(D)J Recombination Reactions Cause Leukaemia
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Applications accepted all year round

Funding Type

PhD Type

V(D)J recombination generates a highly diverse set of immunoglobulin and T cell receptor genes to enable vertebrates to fight a vast range of infections.
  The Eco-Immunology of Wild Mice
  Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

The immune responses that wild animals make contribute to their fitness, but what those immune responses are – and how they differ from those of laboratory animals – is hardly known.
  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
  Single-cell proteomic analysis of host-factor cleavage during norovirus infection
  Dr E Emmott, Dr M Iturriza
Applications accepted all year round

Funding Type

PhD Type

Human norovirus is a major human pathogen, and the causative agent behind ‘winter vomiting disease’. Typically, infection is self-limited, causing diarrhoea and vomiting lasting from 24-72 hours.
  The role of pore-forming bacterial proteins in pneumonia and meningitis
  Prof T J Mitchell, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

The bacterium Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of most children and some adults without causing disease.
  Defining protein degradation machinery in the endoplasmic reticulum underlying resistance mechanisms in cancer
  Assoc Prof J Christianson, Prof Udo Oppermann
Application Deadline: 3 March 2020

Funding Type

PhD Type

Cellular stress is a hallmark of cancers. The restorative homeostatic response mechanisms that often become constitutively engaged, serve to adapt populations to hyperproliferative and metabolically dysregulated states, stabilise malignancy, and elevate resistance to therapeutic agents.
  Structural and functional characterisation of a novel cyanobacterial nanocompartment
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Increasing efficiency is an important driving force behind cellular organization and often achieved through compartmentalization.
  PhD Positions in Cancer Research

Funding Type

PhD Type

Are you looking for excellent research opportunities for your PhD studies at the forefront of cancer research? The German Cancer Research Center (DKFZ)…
  (WIS) Deciphering escape from senescence in vivo
  Prof P Townsend, Prof A D Whetton
Application Deadline: 6 March 2020

Funding Type

PhD Type

Senescence is a dynamic cellular state characterised by a prolonged and generally irreversible cell-cycle arrest that promotes tissue remodelling but it can also have detrimental implications on regenerative capacities of tissues and conduce to inflammation and the progression of ageing-related disease including cancer.
  Understanding and combatting antimicrobial resistance plasmids
  Dr M Buckner, Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a major crisis for human medicine. Globally, untreatable bacterial infections are rapidly increasing, leaving us with limited treatment options.
  Comparative studies of wound and cancer inflammation in plants and animals
  Prof P B Martin
Applications accepted all year round

Funding Type

PhD Type

All organisms need to be able to repair wounds. A key aspect of this is combating the potential for infection when barrier layers are breached by tissue damage.
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
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