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We have 23 Immunology (equality) PhD Projects, Programmes & Scholarships

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Immunology (equality) PhD Projects, Programmes & Scholarships

We have 23 Immunology (equality) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Diagnostics for FMF patients and carrier survival in pandemics

Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Dysfunctional antifungal potency of the respiratory mucosa in COPD

Inhalation of Aspergillus fumigatus spores cause >3,000,000 chronic and >200,000 invasive diseases annually worldwide. Invasive aspergillosis carries a 50% mortality rate overall, but mortality rate approaches 100% if diagnosis is delayed or missed and it is >75% in certain cohorts of patients, such as COPD sufferers. Read more

Investigating the genetic basis of immunological overlap between inflammatory diseases

Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more

Circadian mechanisms in psoriasis: therapeutic opportunities

Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more

Self funded MSc by Research or PhD in Biology: Ion channel signalling in cancer cells

Lead supervisor: Dr W Brackenbury. The student will be registered with the Department of Biology. Our cells constantly sense and transport ions present in their environment. Read more

B cell responses during tumour development

The body remains free of infections and disease due to the cascade of actions of the cells and organs of our immune system. During tumour development, tumours induce changes within the local environment and in downstream locations, such as the lymph nodes. Read more
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