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Immunology PhD Projects, Programs & Scholarships

We have 316 Immunology PhD Projects, Programs & Scholarships

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We have 316 Immunology PhD Projects, Programs & Scholarships

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Exploit the impact of disease-causing HLA variants on cellular phenotypes

The 4 Mb major histocompatibility (MHC) region on chromosome region 6p21.3, which contains the human leukocyte antigen (HLA) complex, plays a vital role in our immune system and is of great importance to many areas of medicine, from organ transplantation and disease diagnosis to cancer immunotherapy. Read more

Spatiotemporal regulation of adaptive immune responses; defining the molecular and cellular basis for immunity against infectious diseases

The adaptive immune system provides protection against a wide range of pathogenic microbes. In its most basic level, this system is effective because it developed the capacity to evolve through spontaneous gene mutations, leading to the generation of an enormous repertoire of B and T cells. Read more

Molecular regulation of neutrophil development in inflammation

Neutrophils are important effector cells of the innate immune system and are produced in large numbers in the bone marrow (BM) through stepwise differentiation of myeloid progenitors, featuring distinct morphological changes and stage-specific expression pattern of surface receptors (1). Read more

Function of CD8 T Cell communication during autoimmunity.

We are interested in understanding how cells of the adaptive immune system, called CD8 T cells, are recruited and organised in space and time in vivo in health and disease (1,2). Read more

Understanding complement system dysregulation in the tumour microenvironment

Inducing a stress response analogous to anti-viral immunity is important for maximising immune responses against the tumour. However, tumours evolve evasion strategies that can limit these responses. Read more

Understanding the effects of immunomodulatory therapies on radiation response

Radiotherapy can ablate tumours through inducing both DNA damage and anti-tumour inflammatory responses. However, innate immunity pathways mounting inflammatory responses can also afford cell intrinsic radioresistance. Read more

Ubiquitin signalling in the pathogenesis and radiotherapy of glioblastoma

Glioblastoma accounts for more than 4000 deaths every year in the UK. The cornerstone of glioblastoma treatment is constituted by maximal surgical resection, radiotherapy and chemotherapy. Read more

High dimensional predictive inference for precision immunotherapy of mesothelioma

Wellcome Trust Studentship. Project. Immunotherapy has transformed the treatment of cancer over the last decade. Mesothelioma, a lethal cancer caused by asbestos responds to immunotherapy, however only a fraction of patients benefit, for reasons which are currently unknown. Read more

Analysing gene expression and blood cells

Using large-scale single cell RNAseq to dissect the genetic architecture of haematopoiesis and investigate implications for Bone Marrow Failure Syndrome and other complex diseases. Read more

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