University of Leeds Immunology PhD Projects, Programmes & Scholarships

We have 12 University of Leeds Immunology PhD Projects, Programmes & Scholarships

NIHR Leeds BRC: Utilising genetic and genomic predictors of vasculitis and disease/treatment complications for application in routine clinical practice

University of Leeds Faculty of Medicine and Health

There is substantial interest in using genetic biomarkers to predict those most at risk of disease and treatment complications; this is one of the focuses of Our Future Health, a national study aiming to recruit 5M participants ( https://ourfuturehealth.org.uk/ ). Read more

Supervisors: Prof A Morgan, Dr MM Iles, Dr R Mujica-Mota

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Unravelling the pre-clinical immunology of the IL-23/1L-17 axis in axial inflammation in psoriatic arthritis towards optimal disease prevention

University of Leeds Faculty of Medicine and Health

Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are key disorders within the seronegative spondylarthropathy (SpA) that was first described in… Read more

Supervisors: Prof D McGonagle, Dr H Marzo-Ortego, Dr T Macleod

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: The role of target organs in initiation of autoimmunity in systemic lupus erythematosus

University of Leeds Faculty of Medicine and Health

Autoimmune diseases such as SLE have traditionally been understood to result from aberrant haematopoietic adaptive immune system that targets normal tissues such as the skin and joints. Read more

Supervisor: Dr E Vital

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: An interferon diagnostic to inform early detection and prevention strategies in Ana positive CTDs

University of Leeds Faculty of Medicine and Health

Type I interferons (IFN) play a role in a wide range of rheumatic and musculoskeletal diseases (RMDs), and strong evidence suggests that measurement of IFN activity could have clinical value, although testing has not progressed into clinical settings. Read more

Supervisors: Dr F Del Galdo, Dr R Ross

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.

University of Leeds Faculty of Medicine and Health

Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more

Supervisors: Prof D Peckham, Prof D Jayne, Dr S Savic, Miss LR Caley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Complex 3D modelling of the tumour microenvironment for immunotherapy combination screening

University of Leeds Faculty of Medicine and Health

Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Read more

Supervisors: Dr MA Volpato, Dr F Errington-Mais

Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

University of Leeds Faculty of Medicine and Health

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

Supervisors: Dr M Lorger, Dr R Salmond

Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Killing Cancer using Dead Virus

University of Leeds Faculty of Medicine and Health

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

Supervisors: Dr S Griffin, Dr A Samson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more

Supervisors: Dr F Errington-Mais, Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 12 University of Leeds Immunology PhD Projects, Programmes & Scholarships

University of Leeds Immunology PhD Projects, Programmes & Scholarships

We have 12 University of Leeds Immunology PhD Projects, Programmes & Scholarships

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