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Immunology (genomic) PhD Projects, Programmes & Scholarships
We have 9 Immunology (genomic) PhD Projects, Programmes & Scholarships
We have 9 Immunology (genomic) PhD Projects, Programmes & Scholarships
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Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease
Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more
Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
Research Group:
School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more
Statistical genetics approaches to investigate autoimmune inflammatory muscle disease for precision medicine
Keywords. statistical genetics, precision medicine, autoimmune, idiopathic inflammatory myopathies, myositis, disease classification, machine learning. Read more
Investigating the role of the microenvironment in paediatric and adult acute myeloid leukaemia
The incidence of acute myeloid leukaemia (AML) increases with age, and in childhood accounts for 20% of all leukaemia. The current overall survival rate in children is only 60-70%, and thereafter falls progressively with age to 5-15% in the elderly. Read more
Functional dissection of disease associated genetic loci in rheumatoid arthritis
Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by inflammation of the joints and has a high socioeconomic burden. Read more
Last chance to apply
Genome Diversification in Cancer and Adaptive Immunity
Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more
Last chance to apply
Genome Diversification in Cancer and Adaptive Immunity
Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more
How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more
The evolution of antimicrobial resistance in human infections
Antibiotics are our main defence against bacterial infections, but rising levels of resistance risks rendering antibiotics ineffective. Read more
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