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Immunology (genomic) PhD Projects, Programmes & Scholarships

We have 12 Immunology (genomic) PhD Projects, Programmes & Scholarships

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We have 12 Immunology (genomic) PhD Projects, Programmes & Scholarships

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Immunogenetics and the carriage of meningococcal bacteria

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more

Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease

Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more

Development of new therapies for immunothrombotic disease.

The Preston lab (www.prestonlab.com) at RCSI is seeking to recruit 2 x PhD students to join an SFI-funded research programme studying molecular pathways at the interface of blood coagulation and innate immunity. Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

  Research Group: School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Investigating the role of the microenvironment in paediatric and adult acute myeloid leukaemia

The incidence of acute myeloid leukaemia (AML) increases with age, and in childhood accounts for 20% of all leukaemia. The current overall survival rate in children is only 60-70%, and thereafter falls progressively with age to 5-15% in the elderly. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more
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