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University of Birmingham, Institute of Cancer and Genomic Sciences PhD Projects, Programs & Scholarships
We have 6 University of Birmingham, Institute of Cancer and Genomic Sciences PhD Projects, Programs & Scholarships
We have 6 University of Birmingham, Institute of Cancer and Genomic Sciences PhD Projects, Programs & Scholarships
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Design and analysis of randomised trials with imperfect dichotomous outcomes
Researchers conducting a randomised trial can be faced with the choice of using an expensive error-free outcome measure or a less-costly but less precise alternative. Read more
OPTI-EX: Optimising exercise interventions for people at risk of dementia
The prevalence of dementia continues to rise, and effective strategies are needed to prevent, delay, or slow its progression. Increased physical activity is thought to facilitate healthy brain ageing and reduce the risk of dementia (Calverley et al., 2020). Read more
A methodological framework for incorporating multiple outcomes into hybrid implementation and effectiveness trials
Many policies are adopted into practice without a solid evidence. Rigorous randomised trials are therefore needed to inform decisions about the implementation of policy interventions. Read more
A methodological framework for interpreting statistical results in randomised clinical trials
Frequentist inference is the most commonly used analysis method in randomised trials. Whilst guidelines for reporting underscore the importance of the interpretation of treatment effects supported by confidence intervals, most ultimately interpret the primary outcome based on statistical significance. Read more
Coordination between RNAPII transcription and DNA replication
RNA Pol II (RNAPII) transcription and DNA replication are the two essential-for-life processes that use as a substrate the DNA in our cells, allowing the¬¬m to express the content of their genetic information and to propagate these instructions to daughter cells. Read more
Regulation of host cell DNA damage response pathways by adenovirus
Human adenoviruses are small non-enveloped viruses with a linear, double-stranded DNA genome. Adenovirus has long served as a faithful model for dissecting the molecular basis of key cellular signalling pathways that regulate fundamental biological processes such as cell growth, cell differentiation and cell death. Read more
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