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University of Liverpool, Institute of Integrative Biology PhD Projects, Programs & Scholarships

We have 24 University of Liverpool, Institute of Integrative Biology PhD Projects, Programs & Scholarships

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Research excellence at University of Liverpool University of Liverpool
Institution Profile
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
University of Liverpool Institute of Integrative Biology
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round
Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
Details
Type/Funding
  Bioengineering of bacterial CO2-concentrating system for improved photosynthesis
University of Liverpool Institute of Integrative Biology
  Dr LN Liu, Dr D Canniffe
Applications accepted all year round
The single-cell photosynthetic bacteria, cyanobacteria, account for over 25% of global carbon fixation, thanks for their powerful CO2-concentrating machinery.
Details
Type/Funding
  Characterising and repurposing cyanobacterial CO2-fixing organelles for metabolic engineering
University of Liverpool Institute of Integrative Biology
  Dr LN Liu, Dr J Hartwell
Applications accepted all year round
Compartmentalisation represents an effective strategy used by cells to enhance their activities. By creating physical barriers and compartments, cells sequester the metabolic pathways from the cellular milieu to allow controls of metabolic flux and toxic diffusion.
Details
Type/Funding
  Climate change and the evolution of insect mating systems
University of Liverpool Institute of Integrative Biology
  Dr SJ Cornell, Dr T Price
Applications accepted all year round
The pervasiveness among animal species of polyandry – i.e., females mating with multiple males – perplexes evolutionary biologists, because it is costly to females (e.g.
Details
Type/Funding
  Elucidation of the role of newly discovered post-translational modification of proteins involved in hypoxia signalling using proteomic analysis and live cell imaging
University of Liverpool Institute of Integrative Biology
  Dr V See, Prof C E Eyers
Applications accepted all year round
The hypoxia signalling pathway is required for the adaptation of cells to a low oxygen environment, which cells can experience in various physiological and pathological circumstances related to high altitude, development, wound healing and cancer.
Details
Type/Funding
  Evolutionary insights for engineering improved globin oxygen carriers
University of Liverpool Institute of Integrative Biology
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round
Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
Details
Type/Funding
  Examining the host-environmental interface of Histoplasma capsulatum to understand the implications of disease management within endemic populations.
University of Liverpool Institute of Integrative Biology
  Dr C Scantlebury, Prof A J McCarthy, Dr T Helgason
Applications accepted all year round
Histoplasmosis is an endemic disease with serious consequences to equine and human health. This dimorphic fungus favours nitrogen rich environments, and generates highly resistant spores.
Details
Type/Funding
  Exploiting advanced methods for protein structure prediction
University of Liverpool Institute of Integrative Biology
  Dr D J Rigden, Dr R Keegan
Applications accepted all year round
Protein structural information is crucial for an understanding of protein function and evolution. Currently, there is only experimental data for a tiny fraction of the protein universe.
Details
Type/Funding
  Exploring Stem Cell Regulation by Heparan Sulphates using Chemical Biology and Glycomics Strategies
University of Liverpool Institute of Integrative Biology
  Prof J E Turnbull
Applications accepted all year round
Heparan sulphates (HS) are complex sulphated polysaccharides expressed at the cell surface. They are essential co-receptors for many proteins, most notably many signalling growth factors, and they act as dynamic regulators of protein function.
Details
Type/Funding
  Exploring the role of meiotic proteins in cancer
University of Liverpool Institute of Integrative Biology
  Dr U McClurg
Applications accepted all year round
Cancer is one of the main causes of death worldwide. The main challenge is the development of treatments specifically targeting cancers without killing healthy cells.
Details
Type/Funding
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