We have 23 University of Liverpool, Institute of Life Course and Medical Sciences PhD Projects, Programmes & Scholarships

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Institute of Life Course and Medical Sciences  University of Liverpool

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University of Liverpool, Institute of Life Course and Medical Sciences PhD Projects, Programmes & Scholarships

We have 23 University of Liverpool, Institute of Life Course and Medical Sciences PhD Projects, Programmes & Scholarships

Remote ischaemic conditioning: a novel approach to reduce hypertrophy?

Cardiac hypertrophy is a significant clinical issue. Enlargement of the heart caused by hypertension, injury or other disease, can cause increased muscle mass, increased fibrous tissue and lead to poor function, stiffer hearts and ultimately heart failure. Read more

Uncovering the role of RARɣ in mouse embryonic development using gastruloids

The three retinoic acid receptors (RAR), RARα, RARβ, RARɣ, are transcription factors that control gene expression and cell fate following their activation by all-trans retinoic acid (ATRA), the active metabolite of vitamin A. Read more

Investigating the role of Aquaporins in age related diseases

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more
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Repeat Physical Traumas an initiator for motor neuron disease (MND): an insight from professional rugby

Motor Neuron Disease (MND) is a devastating condition affecting neuronal cells responsible for voluntary muscle movement. The risk of developing MND is 1 in 300, predominantly in individuals over 50. Read more

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Morphology, motion, and mechanics of vertebral joints in fish

We depend on healthy joints to stay active, independent and productive. Disorders of the joints of our spine (intervertebral joints) are particularly disruptive, with back pain and disorders impacting millions of people. Read more

Control of bone shape and function by the extracellular matrix Fibrillin-1

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more

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