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We have 18 University of Liverpool, Institute of Systems, Molecular and Integrative Biology PhD Projects, Programmes & Scholarships

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Institute of Systems, Molecular and Integrative Biology  University of Liverpool

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University of Liverpool, Institute of Systems, Molecular and Integrative Biology PhD Projects, Programmes & Scholarships

We have 18 University of Liverpool, Institute of Systems, Molecular and Integrative Biology PhD Projects, Programmes & Scholarships

Mathematical Modelling of Cell Shape and Localised Cell growth.

The correct cell shape is essential for proper cell function. For example, in the brain signalling between neurons is received by dendritic spines, Dendritic spines are protrusions on the surface of the neuron, they come in different shapes, the most well-known being mushroom shaped. Read more

Conjugated polymer nanoparticles for fluorescence-guided intraoperative tumour visualization

Every year there are 900,000 new cases of head and neck cancer (HNC) worldwide. Unfortunately, the number of people being diagnosed and dying of this disease in Liverpool is significantly higher than the rest of England, and in some deprived areas, higher than parts of India and South Africa. Read more

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Investigating how tumour associated macrophages affect cancer metastasis and response to therapies

Solid tumours are generally highly infiltrated by macrophages. Macrophages are heterogeneous and different populations with different and sometimes even opposite functions co-exist in tumours affecting cancer progression. Read more

Biological pathways supporting the formation and function of chromatin (Scholarship)

Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by histone proteins, their role in packaging DNA into chromatin and the “epigenetic” information they carry. Read more

Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

The world is getting hotter and drier due to climate change, and the human population is growing rapidly. Furthermore, it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more