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PhD Projects, Programs & Scholarships in Ireland

We have 104 PhD Projects, Programs & Scholarships in Ireland

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  KETOGENIC DIET: An in vitro single-cell imaging and molecular analysis approach to determine and therapeutically target the control principles of neuronal bioenergetics for the treatment of epilepsy with ketogenic diet
  Prof J Prehn
Applications accepted all year round

Funding Type

PhD Type

Glutamate is the main excitatory neurotransmitter in the central nervous system (CNS)CNS. Glutamate receptor activation imposes a significant work load and energy demand on neurons which requires neurons to increase ATP production.
  Mechanisms of fever-induced epilepsy and related cognitive impairment
  Dr G Brennan, Prof D Henshall
Applications accepted all year round

Funding Type

PhD Type

Temporal-lobe epilepsy is a common chronic neurological disorder characterized by spontaneous recurrent seizures. Fever-induced seizures (febrile seizures) are the most common type of seizure in young children and are generally harmless.
  Modelling metastasis in 3D: from pathway discovery towards targeted drugs
  Dr O Piskareva, Prof J Prehn
Applications accepted all year round

Funding Type

PhD Type

Paediatric cancer research in general and neuroblastoma, in particular,has very limited preclinical models of metastasis.
  Modelling tumour – immune system interactions in 3D in vitro model of neuroblastoma using collagen-based scaffolds
  Dr O Piskareva, Dr C Curtain, Dr F O'Brien, Prof D O'Shea
Applications accepted all year round

Funding Type

PhD Type

The main challenge in treating neuroblastoma, a paediatric cancer of the sympathetic nervous system, is to combat tumour metastasis and resistance to multiple chemotherapeutic drugs highlighting the unmet need in new more efficient pre-clinical models to study disease pathogenesis, drugs testing and development.
  Modification of marketed dosage forms for administration to children
  Dr F O'Brien, Dr M Peak
Applications accepted all year round

Funding Type

PhD Type

Can guidance be provided to allow pharmaceutical companies to develop approvable strategies for alternative methods of administration of medicines to children when the marketed dosage form does not provide the required dose and/or is not acceptable to the child or carers?.
  Molecular mechanisms of blood-brain barrier dysfunction and repair in epilepsy
  Dr C Ruedell Reschke, Prof D Henshall
Applications accepted all year round

Funding Type

PhD Type

Epilepsy is a common, chronic neurological disorder characterized by recurrent, unprovoked seizures. Current treatments fail at least one third of patients and we have no diseasemodifying therapies.
  Multi-antibiotic resistant Enterobacteriaceae and near-patient environmental decontamination: are current methods adequate in the face of changing epidemiology and enhanced transmission
  Dr D Fitzgerald-Hughes
Applications accepted all year round

Funding Type

PhD Type

Patients with infections caused by antibiotic-resistant bacteria are at increased risk of worse clinical outcomes and death.
  Non-viral gene therapy to prevent cartilage degeneration in Osteoarthritis
  Dr C Curtain, Dr O Kennedy, Dr F O'Brien
Applications accepted all year round

Funding Type

PhD Type

Osteoarthritis (OA) is the most common form of joint disease, affecting one in five people in the EU and results in activity limitations for approximately one in ten.
  Novel antibiotic candidates against drug-resistant bacteria causing the highest threat to human health
  Prof M Devocelle, Dr D Fitzgerald-Hughes
Applications accepted all year round

Funding Type

PhD Type

‘A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century ‘, reported the World Health Organisation (WHO) in 2015.
  Novel approaches for the treatment of dry eye disease
  Dr J Gabhann, Prof C Murphy
Applications accepted all year round

Funding Type

PhD Type

Inflammation is a key unifying factor for a range of ocular surface inflammatory diseases including autoimmune mediated dry eye disease (DED) and complications with corneal transplantation (CT).
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