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Cancer / Oncology PhD Projects, Programs & Scholarships in Ireland

We have 15 Cancer / Oncology PhD Projects, Programs & Scholarships in Ireland

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  A key role for FKBPL in the regulation of cancer stem cell signalling and the microenvironment; therapeutic implications for tumour growth and metastasis
  Prof T Robson, Prof D O'Connor
Applications accepted all year round

Funding Type

PhD Type

Cancer stem cells (CSCs) are a special type of cell found within tumours that are able to undergo unlimited self-renewal and are highly resistant to therapy.
  Bioorthogonal Chemistry and Fluorescent Post-Labeling for Real-Time Tracking of a Platinum-based Anticancer Drug
  Dr D Griffith, Dr D O’Shea
Applications accepted all year round

Funding Type

PhD Type

Metal-based drugs have a wide range of medicinal applications and are routinely used clinically as therapeutic and diagnostic agents.
  Developing, piloting and evaluating a theoretical-based intervention to support endocrine therapy medication taking behaviour in women with stage I-III breast cancer
  Prof K Bennett, Dr C Cahir
Applications accepted all year round

Funding Type

PhD Type

Almost 3,000 women are diagnosed with breast cancer annually in Ireland. In women with hormone-responsive early breast cancer, 5-10 years of endocrine therapy is recommended to prevent breast cancer recurrence and mortality, with a reduction in cancer recurrence of up to 50%.
  Development of “FXR-targeted” Nutraceuticals for Treatment of Intestinal Diseases
  Prof S Keely, Dr S Das
Applications accepted all year round

Funding Type

PhD Type

The incidence of intestinal diseases, such as colorectal cancer (CRC) and inflammatory bowel disease (IBD), is significantly higher in Western societies than elsewhere in the world.
  RET a novel therapeutic target to treat breast cancer brain metastasis
  Prof L Young, Dr A Hill
Applications accepted all year round

Funding Type

PhD Type

Metastatic disease recurrence occurs in up to 30% of breast cancer patients with approximately 20% of these tumours metastasising to the brain.
  The role of USP11 in ER+ Breast Cancer
  Prof D O'Connor, Prof T Robson
Applications accepted all year round

Funding Type

PhD Type

De-regulated estrogen receptor (ER) function is a key feature of approximately 70% of breast cancers. Given that the tumourigenic properties of ER primarily lie in its function as a growth-controlling transcription factor, we sought to discover novel modulators of ER transcriptional activity.
  The spleen as a site of relapse for early T-cell progenitor leukaemia
  Dr T Chonghaile, Prof J Prehn
Applications accepted all year round

Funding Type

PhD Type

Early T-cell progenitor ALL (ETP-ALL) originates from a block at early stages of T-cell development, has a poor prognosis with risk for relapse.
  Theranostic Combination of Targeted Fluorescence Imaging and Photodynamic Therapy
  Dr D O’Shea, Dr B Murphy
Applications accepted all year round

Funding Type

PhD Type

Research Project Description. Photodynamic therapy (PDT) is a modern treatment that uses light to locally photosensitize tissues, resulting in the selective killing of targeted cells.
  Unveiling mechanisms of differentiation in neuroblastoma: from pathway discovery towards epigenetic-targeted drugs
  Dr O Piskareva
Application Deadline: 29 May 2020

Funding Type

PhD Type

Cell fate determination and differentiation are processes that are crucial in developmental biology, which assigns cells their functional roles and gives them a unique identity.
  Our Mission: to Educate, Nurture and Discover for the benefit of Human Health

Funding Type

PhD Type

Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland.
  Deciphering the role of the tumour suppressor Hippo pro-apoptotic network in cancer
  Dr D Gomez
Application Deadline: 22 June 2020

Funding Type

PhD Type

At SBI we believe that studying the dynamic control of cell-signalling is key for understanding many diseases, including cancer.
  Emerging hypoxic signalling in human cancers
  Dr S Rey
Application Deadline: 22 June 2020

Funding Type

PhD Type

Our goal is to elucidate novel mechanisms of oxygen sensing in cancer cells. In particular, the student will focus upon exploring hypoxia- inducible factor (HIF)-α independent mechanisms, with potential implications for targeted cancer therapies aimed at decreasing recurrence, resistance and metastasis.
  Mathematical modelling of cancer signalling for precision medicine
  Dr D Fey
Application Deadline: 22 June 2020

Funding Type

PhD Type

Cells process intra- and extracellular signals to make vital cell-fate decisions. In diseases such as cancer, these decisions go awry due to the dysregulation of the intracellular communication networks.
  Novel mechanisms of hypoxic metabolic reprogramming in metastatic cancers
  Dr L Schito
Application Deadline: 22 June 2020

Funding Type

PhD Type

Hypoxia, a common feature of most human cancers, activates a multifaceted transcriptional, post-transcriptional, translational and epigenetic adaptive program that allows cancer cells to reprogram their metabolism in order to survive the unfavourable conditions of the tumor microenvironment, and subsequently metastasize to secondary sites.
  The role of syndecan-4 as a regulator of the tumour microenvironment in pancreatic cancer
  Dr S Thorpe
Application Deadline: 22 June 2020

Funding Type

PhD Type

This research project will assess the role of syndecan-4 in pancreatic cancer progression. Despite its relatively low prevalence, pancreatic cancer is the 5th leading cause of cancer-related mortality and will claim approx.
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