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We have 21 Chemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Jordanstown

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Chemistry

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Jordanstown  United Kingdom

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Chemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Jordanstown

We have 21 Chemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Jordanstown

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Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery

Lipid nanocapsules (LNCs) are very interesting nanoformulations as they can be made by phase inversion technique (PIT), a scalable method with predictable particle size at the beginning of the preparation process. Read more

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Dissecting mechanism of drug responses to novel anti-cancer therapies

Repurposing drug screens with compounds that have already gained FDA approval can accelerate the identification of new therapies to treat an illness and in the cancer setting extend life or provide compassionate care. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Chemical glycoengineering of therapeutic antibodies

Glycosylation is the most common posttranslational protein modification. Recombinant therapeutic glycoproteins (RTGs) such as monoclonal antibodies (mAbs) are decorated with complex glycans that determine not only their efficacy but also other critical parameters such as in vivo half-life, stability and antigenicity. Read more

Bio-inspired liquid-like coatings for medical devices to combat biofilms and associated infections

Biofilms are microbial cells embedded within a self-secreted extracellular polymeric substance matrix, which are central to some of the most urgent global challenges across diverse fields of application, from medicine to industry and exert considerable economic and social impact. Read more

Mechanochemical synthesis of polymer-drug conjugates via reactive extrusion

Polymer–drug conjugate (PDCs) therapeutics are pharmacologically active macromolecular constructs comprising at least one therapeutic agent covalently bound to a polymeric carrier. Read more

Self-regulating, self-cleaning biomaterials

A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more

Enzyme-responsive peptide hydrogel as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

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